Results 71 to 80 of about 9,650,037 (303)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

A Hierarchical P2PSIP Architecture to Support Skype-like Services [PDF]

open access: yes, 2009
A hierarchical DHT overlay architecture based on P2PSIP is proposed to support a skype-like service. The IETF P2PSIP working group is standardizing a protocol to support any DHT in order to deploy services inside a domain.
Guerrero López, María Carmen   +9 more
core   +1 more source

Hierachical Arabic Phoneme Recognition using MFCC Analysis [PDF]

open access: yesIraqi Journal for Electrical and Electronic Engineering, 2007
In this paper, a hierarchical Arabic phoneme recognition system is proposed in which Mel FrequencyCepstrum Coefficients (MFCC) features is used to train the hierarchical neural networks architecture.Here, separate neural networks (subnetworks) are to be ...
Abduladhem Abdulkareem Ali, I. T. Hwaidy
doaj  

PLAYOUT — A Hierarchical Layout System [PDF]

open access: yes, 1988
Very Large Scale Intergration (VLSI) has become a technology of large economical importance. Mastering of this technology on one hand means the latest semiconductor processing technology, on the other hand computer aided design. Whereas the first is a problem for physics and chemistry, the progress in the second field results from large activities in ...
openaire   +2 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Examining the limits of the Condorcet Jury Theorem: Tradeoffs in hierarchical information aggregation systems

open access: yesCollective Intelligence, 2022
Condorcet’s Jury Theorem states that the correct outcome is reached in direct majority voting systems with sufficiently large electorates as long as each voter’s independent probability of voting for that outcome is greater than 1/2.
Lucas Böttcher, Georgia Kernell
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Analytical Evaluation of Hierarchical Planning Systems [PDF]

open access: yes, 1984
Hierarchical planning systems have become popular for multilevel decision problems. After reviewing the concept of hierarchical planning and citing some examples, the authors describe a method for analytic evaluation of a hierarchical planning system ...
Dempster, M.A.H.   +5 more
core   +1 more source

Control and Coordination in Hierarchical Systems [PDF]

open access: yes, 1980
This book presents the applied theory of control and cooordination in hierarchical systems which are those where decision making has been divided in a certain way. It concentrates on various aspects of optimal control in large scale systems and covers a
Findeisen, W.   +5 more
core   +1 more source

Urban Wind Energy Assessment Using Machine Learning and Multi-criteria Analysis

open access: yesTecnoLógicas
The transition toward renewable energy sources in urban environments presents technical and strategic challenges due to the variability of available resources and the inherent constraints of built-up spaces.
Gianina Garrido-Silva   +3 more
doaj   +1 more source

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