Results 81 to 90 of about 9,650,037 (303)

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Hierarchical games and their applications in reasoning about reactive systems

open access: yes, 2010
We present a unified game-based approach for branching-time model checking of hierarchical systems. Such systems are exponentially more succinct than standard state-transition graphs, as repeated sub-systems are described only once.
MURANO, ANIELLO, O. Kupferman
core  

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

A hierarchical multi-label classification ant colony algorithm for protein function prediction [PDF]

open access: yes, 2010
This paper proposes a novel ant colony optimisation (ACO) algorithm tailored for the hierarchical multi-label classification problem of protein function prediction.
Otero, Fernando E.B.   +5 more
core   +1 more source

Hierarchical Blockchain Energy Trading Platform and Microgrid Management Optimization

open access: yesEnergies
In this paper, we describe a solution that has been developed to create an intelligent software platform for the optimal management of energy trade (specifically a P2P trade) in microgrids.
Kristián Košt’ál   +2 more
doaj   +1 more source

Multiple parallel fuzzy expert systems utilizing a hierarchical fuzz model

open access: yesAgricultural Economics (AGRICECON), 2007
Business, economic, and agricultural YES-or-NO decision making problems often require multiple, different and specific expertises. This is due to the nature of such problems in which decisions may be influenced by multiple different, relevant aspects ...
S. Aly, I. Vrana
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Hierarchical location-allocation models for congested systems [PDF]

open access: yes
In this paper we address the issue of locating hierarchical facilities in the presence of congestion. Two hierarchical models are presented, where lower level servers attend requests first, and then, some of the served customers are referred to higher ...
Daniel Serra, Vladimir Marianov
core  

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

A hierarchical coordinated control strategy of air‐conditioning loads for peak regulation service

open access: yesIET Generation, Transmission & Distribution
The increased penetration of renewable energy sources and the intensification of peak‐valley differences present challenges to peak regulation in the power system.
Wei Wang   +7 more
doaj   +1 more source

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