Results 61 to 70 of about 2,771,947 (386)

On a class of reductions of Manakov-Santini hierarchy connected with the interpolating system

open access: yes, 2009
Using Lax-Sato formulation of Manakov-Santini hierarchy, we introduce a class of reductions, such that zero order reduction of this class corresponds to dKP hierarchy, and the first order reduction gives the hierarchy associated with the interpolating ...
Bogdanov L V   +7 more
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Atypical functional connectome hierarchy in autism

open access: yesNature Communications, 2018
One paradox of autism is the co-occurrence of deficits in sensory and higher-order socio-cognitive processing. Here, we examined whether these phenotypical patterns may relate to an overarching system-level imbalance—specifically a disruption in ...
Seokjun Hong   +10 more
semanticscholar   +1 more source

Towards a description of the double ramification hierarchy for Witten's $r$-spin class

open access: yes, 2015
The double ramification hierarchy is a new integrable hierarchy of hamiltonian PDEs introduced recently by the first author. It is associated to an arbitrary given cohomological field theory.
Buryak, Alexandr, Guéré, Jérémy
core   +2 more sources

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

The Potential of Digital Storytelling as an Ethnographic Research Technique in Social Sciences

open access: yesCultural Science, 2015
By using ethnographic research techniques, we can ask questions in order to understandsome issues in the social sciences such as experience, the unique, the ordinary, daily life, emotions etc.
Oğuz Hatice Şule
doaj   +1 more source

Ladderpath Approach: How Tinkering and Reuse Increase Complexity and Information

open access: yesEntropy, 2022
The notion of information and complexity are important concepts in many scientific fields such as molecular biology, evolutionary theory and exobiology. Many measures of these quantities are either difficult to compute, rely on the statistical notion of ...
Yu Liu, Zengru Di, Philip Gerlee
doaj   +1 more source

Topological insulators and superconductors: tenfold way and dimensional hierarchy [PDF]

open access: yes, 2009
It has recently been shown that in every spatial dimension there exist precisely five distinct classes of topological insulators or superconductors. Within a given class, the different topological sectors can be distinguished, depending on the case, by a
S. Ryu   +3 more
semanticscholar   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Genomic analysis reveals a tight link between transcription factor dynamics and regulatory network architecture

open access: yesMolecular Systems Biology, 2009
Although several studies have provided important insights into the general principles of biological networks, the link between network organization and the genome‐scale dynamics of the underlying entities (genes, mRNAs, and proteins) and its role in ...
Raja Jothi   +7 more
doaj   +1 more source

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