Results 251 to 260 of about 34,892 (283)

Hypoxia Inducible Factor pathway proteins in high-altitude mammals

Trends in Biochemical Sciences
Humans and other mammals inhabit hypoxic high-altitude locales. In many of these species, genes under positive selection include ones in the Hypoxia Inducible Factor (HIF) pathway. One is PHD2 (EGLN1), which encodes for a key oxygen sensor. Another is HIF2A (EPAS1), which encodes for a PHD2-regulated transcription factor.
openaire   +2 more sources

Cellular adaptation to hypoxia through hypoxia inducible factors and beyond

Nature Reviews Molecular Cell Biology, 2020
Pearl Lee, Navdeep S Chandel, M Celeste Simon   +2 more
exaly  

Broadening horizons: the role of ferroptosis in cancer

Nature Reviews Clinical Oncology, 2021
Xin Chen, Rui Kang, Guido Kroemer
exaly  

Inhibition of hypoxia-inducible factor-2α in renal cell carcinoma with belzutifan: a phase 1 trial and biomarker analysis

Nature Medicine, 2021
Toni K Choueiri, Elizabeth R Plimack, David F Mcdermott   +2 more
exaly  

Hypoxia at High Altitude

BMJ, 1964
openaire   +1 more source

Functional Adaptation to High Altitude Hypoxia

Science, 1975
openaire   +3 more sources

Imaging hypoxia to improve radiotherapy outcome

Nature Reviews Clinical Oncology, 2012
Michael R Horsman, Lise Saksø Mortensen, Morten Busk   +2 more
exaly  

Chemical Design and Synthesis of Functionalized Probes for Imaging and Treating Tumor Hypoxia

Chemical Reviews, 2017
Wen-bo Bu, Jianlin Shi
exaly  

Targeting hypoxia in cancer therapy

Nature Reviews Cancer, 2011
William R Wilson, Michael P Hay
exaly  

Hypoxia — a key regulatory factor in tumour growth

Nature Reviews Cancer, 2002
Adrian L Harris
exaly