Results 71 to 80 of about 34,730 (280)

Transthoracic Electrical Impedance in Cases of High-altitude Hypoxia [PDF]

BMJ, 1974
Changes in transthoracic electrical impedance (T.E.I.) due to high-altitude hypoxia (3,658 m) have been measured in 20 young, healthy Indian soldiers. They were first studied at sea level (198 m) and then rapidly transported by air to 3,658 m, where they were studied daily from day 1 to day 5 and then on days 8 and 10. The mean (+/-S.D.) T.E.I.
S B, Roy, V, Balasubramanian, M R, Khan, V S, Kaushik, S C, Manchanda, S K, Guha   +5 more
openaire   +2 more sources

Microglial Activation Under Hypoxic Conditions in Early Alzheimer's Disease: Can Natural SIRT1 Activators Be Therapeutic Allies in the Inflammation–Energy Axis?

Phytotherapy Research, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative condition characterized by a preclinical stage that typically lasts for decades. Early on during this time, microglia react to pathological changes and become protective and even transiently delay neurodegeneration.
Sara Merlo, Cristiana Lucia Rita Lipari, Aurora Patti, Maria Angela Sortino   +3 more
wiley   +1 more source

Extended longevity at high altitude: Benefits of exposure to chronic hypoxia

BLDE University Journal of Health Sciences, 2017
BACKGROUND: Acute exposure to hypobaric hypoxia can give rise to acute mountain sickness, and rarely, high altitude pulmonary edema, and high altitude cerebral edema. However, with gradual adaptation to “chronic hypoxia”, following the Adaptation to High
Gustavo R Zubieta-Calleja, Natalia A Zubieta-DeUrioste   +1 more
doaj   +1 more source

Convergent Genomic Signatures of High-Altitude Adaptation among Six Independently Evolved Mammals

Animals, 2022
The species living in the Qinghai-Tibet Plateau provide an excellent model system for studying the relationship between molecular convergent evolution and adaptation.
Tianshu Lyu, Shengyang Zhou, Jiaohui Fang, Lidong Wang, Lupeng Shi, Yuehuan Dong, Honghai Zhang   +6 more
doaj   +1 more source

Thromboelastometry and Platelet Function during Acclimatization to High Altitude [PDF]

, 2018
Interaction between hypoxia and coagulation is important given the increased risk of thrombotic diseases in chronically hypoxic patients who reside at sea level and in residents at high altitude.
Baillie, J.K., Barber, M.T., Harrison, P., Horn, E.H., Jackson, A.I.R., MacInnis, M.J., Main, S.E., Moores, C., Nimmo, A.F., Paterson, G.G., Rocke, A.S., Schnopp, M.F., Stannett, C., Thompson, A.A.R.   +13 more
core   +3 more sources

Sympatho‐Excitation in Pulmonary Hypertension: The Potential Role of Pulmonary Arterial Baroreceptors: An Acute Physiologic Intervention Study

Respirology, EarlyView.
Pulmonary arterial baroreceptors reflexively stimulate sympathetic nerve activity (SNA) in response to elevated pulmonary artery pressure and distension. In pulmonary hypertension patients, changes in muscle SNA were proportional to changes in pulmonary haemodynamics following nebulised iloprost.
Michael J. Plunkett, Ana L. C. Sayegh, Robert A. Lewis, Tanya J. McWilliams, Sasiharan Sithamparanathan, Julian F. R. Paton, James P. Fisher   +6 more
wiley   +1 more source

Effects of altitude and exercise intensity on cardiac function in rats

Experimental Physiology
High‐altitude exercise affects cardiac function. This study investigated how altitude and exercise intensity interacted to affect cardiac function of Sprague‐Dawley rats.
Minxia Zhu, Xiaofeng Li, Bing Liu, Jing Guo, Yuanyuan Xiao, Zhiyao Liu, Mengru Duan, Yi Liu   +7 more
doaj   +1 more source

DATA in BRIEF of: Adaptative mechanisms indicated by placental protein expression changes in high-altitude Tibetan women during vaginal delivery

Data in Brief
Over a period of 30,000 to 40,000 years, high-altitude Tibetans have physiologically and genetically adapted to conditions such as hypoxia, low temperature, and high-intensity ultraviolet radiation.
Huifang Liu, Tana Wuren, Ri-li Ge
doaj   +1 more source

Regulation of High-Altitude Hypoxia on the Transcription of CYP450 and UGT1A1 Mediated by PXR and CAR

Frontiers in Pharmacology, 2020
Little is known about what roles the pregnane X receptor (PXR) and constitutive androstane receptor (CAR) play in drug metabolism in high-altitude hypoxia.
Ya-bin Duan, Ya-bin Duan, Jun-bo Zhu, Jun-bo Zhu, Jian-xin Yang, Gui-qin Liu, Xue Bai, Ning Qu, Xue-jun Wang, Xiang-yang Li   +9 more
doaj   +1 more source

Effects of Hyperbaric Hypoxia on Some Enzyme Systems in the Mammalian Liver [PDF]

, 1978
The metabolic effects of hypobaric hypoxic stress on the mammalian liver were studied. The lactate dehydrogenase (LDH) and succinate dehydrogenase (SDH) activity of mouse liver homogenates were measured after exposure to an equivalent altitude of 36,000 ...
Baeyens, Dennis A., Meier, M. J.
core   +2 more sources