Results 81 to 90 of about 34,730 (280)
High‐Altitude Hypoxemia in Adults With Sickle Cell Disease (SCD)
American Journal of Hematology, EarlyView.
Mofiyin A. Obadina +4 more
wiley +1 more source
Cardiovascular Plasticity and Adaptation of High‐Altitude Birds and Mammals
Integrative Zoology, EarlyView.This schematic depicts the cardiovascular adaptations of mammals and birds to high‐altitude hypoxia. It highlights key phenotypic changes in oxygen transport and cardiac responses, driven by molecular mechanisms including transcriptional regulation and genetic modifications.
Huishang She, Yanhua Qu
wiley +1 more source
Ethiopian Native Highlander’s Adaptation to Chronic High‐Altitude Hypoxia
BioMed Research International, 2022 People living in a high‐altitude environment have distinct lifelong challenges. Adaptive mechanisms have allowed high‐altitude residents to survive in a low‐oxygen environment for thousands of years. The purpose of this review was to provide a brief review of the Ethiopian native highlanders’ adaptive mechanisms to chronic hypoxia problems at high ...
openaire +2 more sources
Integrative Zoology, EarlyView.Prenatal hypoxia enhances adult hypoxia tolerance in Brandt's voles, preserving cognitive and memory functions. Transcriptomic analysis reveals adaptive changes in energy metabolism, oxygen transport, and neuroprotective mechanisms, highlighting developmental plasticity.
Mengyang Li +5 more
wiley +1 more source
Frontiers in PharmacologyTourism in high-altitude areas and high-altitude outdoor activities have seen a significant increase, and health threats centered around high-altitude pulmonary edema and high-altitude pulmonary hypertension have become increasingly prominent.
Jiale Song +8 more
doaj +1 more source
Cardiovascular Response to High Altitude Hypoxia
Defence Science Journal, 1984 Normal and abnormal cardiovascular response to high altitude (HA) hypoxia were studied in 98 healthy subjects and in 15 patients with HA pulmonary oedema (HAPO) and acute mountain sickness (AMS) at an altitudeof 3,658 m. The healthy sea level (SL) residents showed marked blood volume changes during the first week with pulmonary hypotension and ...
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Sustained high-altitude hypoxia increases cerebral oxygen metabolism
Journal of Applied Physiology, 2013 Acute mountain sickness (AMS) is a common condition occurring within hours of rapid exposure to high altitude. Despite its frequent occurrence, the pathophysiological mechanisms that underlie the condition remain poorly understood. We investigated the role of cerebral oxygen metabolism (CMRO2) in AMS.
Zachary M, Smith +5 more
openaire +3 more sources
How hypoxia slows fetal growth: insights from high altitude
Pediatric Research, 2021 A continuous oxygen supply is vital for fueling fetal growth, yet we know surprisingly little as to the precise mechanisms by which hypoxia reduces fetal growth. Animal models, while important, are limited by the enormous variability in mammalian physiologic responses to pregnancy. One of the earliest models for understanding hypoxia-induced reductions
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Brain natriuretic peptide and NT-proBNP levels reflect pulmonary artery systolic pressure in trekkers at high altitude. [PDF]
, 2013 Our objective was to evaluate the utility of the natriuretic peptides BNP (brain natriuretic peptide) and NT-proBNP as markers of pulmonary artery systolic pressure (PASP) in trekkers ascending to high altitude (HA). 20 participants had BNP and NT-proBNP
Begley, J +9 more
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Hypoxia-Induced Oxidative Stress Modulation with Physical Activity. [PDF]
, 2017 Increased oxidative stress, defined as an imbalance between prooxidants and antioxidants, resulting in molecular damage and disruption of redox signaling, is associated with numerous pathophysiological processes and known to exacerbate chronic diseases ...
Debevec, T., Millet, G.P., Pialoux, V.
core +3 more sources