Results 61 to 70 of about 854,299 (353)

The Development of Nonalcoholic Fatty Liver Disease and Metabolic Syndromes in Diet-Induced Rodent Models

Life, 2023
Dietary macronutrients are essential for metabolic regulation and insulin function. The present study examined the effects of different high-fat diets (HFDs) and high-carbohydrate diets (HCDs) on the development of non-alcoholic fatty liver disease and ...
Bayan Abdulhafid Aljahdali, Adnan Salem Bajaber, Doha M. Al-Nouri, Abdulrahman Saleh Al-Khalifah, Shaista Arzoo, Abeer Abdullah Alasmari   +5 more
doaj   +1 more source

Making progress on the global crisis of obesity and weight management [PDF]

, 2018
No abstract ...
Astrup, Arne, Lean, Michael E.J., Roberts, Susan B.   +2 more
core   +2 more sources

Similar weight loss with low- or high-carbohydrate diets [PDF]

The American Journal of Clinical Nutrition, 1996
The goal of this study was to evaluate the effect of diets that were equally low in energy but widely different in relative amounts of fat and carbohydrate on body weight during a 6-wk period of hospitalization. Consequently, 43 adult, obese persons were randomly assigned to receive diets containing 4.2 MJ/d (1000 kcal/d) composed of either 32% protein,
A, Golay, A F, Allaz, Y, Morel, N, de Tonnac, S, Tankova, G, Reaven   +5 more
openaire   +2 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

DIET-INDUCED CHANGES IN SOME PARAMETERS OF OXIDATIVE SATUS IN WISTAR RATS – COMPARISON BETWEEN THREE DIFFERENT DIETS AND EFFECTS OF REPLACING DIETARY SUCROSE WITH STEVIOL GLYCOSIDES

Trakia Journal of Sciences
PURPOSE: The aim of the study was to evaluate the effects of a high-fat diet, high-carbohydrate diet and a combined high-fat high-carbohydrate diet on some parameters of oxidative status in a rat experimental model, and to test the potential positive ...
K. Trifonova
doaj   +1 more source

Transcriptomics, metabolomics and histology indicate that high-carbohydrate diet negatively affects the liver health of blunt snout bream (Megalobrama amblycephala)

BMC Genomics, 2017
BackgroundGlobal trend of the introduction of high levels of relatively cheap carbohydrates to reduce the amount of costly protein in the aquatic animal feed production has affected the aquaculture of an economically important cyprinid fish, blunt snout ...
W. Prisingkorn, P. Prathomya, Ivan Jakovlić, Han Liu, Yu-Hua Zhao, Weimin Wang   +5 more
semanticscholar   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

Feeding restriction unalters physiological responses to dietary lipid and carbohydrate levels in juvenile gibel carp (Carassius gibelio)

Aquaculture Reports, 2022
To investigate the physiological responses to different energy sources under feeding restriction in fish, gibel carp were fed a high lipid, low carbohydrate diet (HL diet, 12% lipid, 16% carbohydrate) or a high carbohydrate, low lipid diet (HC diet, 34 ...
Wenjie Xu, Hancheng Geng, Liyun Wu, Junyan Jin, Dong Han, Xiaoming Zhu, Yunxia Yang, Haokun Liu, Shouqi Xie   +8 more
doaj   +1 more source

Impact of High-Carbohydrate Diet on Metabolic Parameters in Patients with Type 2 Diabetes

Nutrients, 2017
In patients with type 2 diabetes mellitus (T2DM), whether dietary carbohydrates have beneficial or detrimental effects on cardiometabolic risk factors has drawn attention.
C. Jung, K. Choi
semanticscholar   +1 more source

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source