Journal of Nobel Medical College, 2018 Introduction: Abnormalities in serum lipid and lipoprotein levels are recognized as major modifiable risk factors for cardiovascular disease and essential hypertension and retinopathy.
Bishwa Nath Adhikari +4 more
doaj +1 more source
High density lipoprotein mimicking nanoparticles for atherosclerosis
Nano Convergence, 2020 Atherosclerosis is a major contributor to many cardiovascular events, including myocardial infarction, ischemic stroke, and peripheral arterial disease, making it the leading cause of death worldwide.
Jun Chen +5 more
doaj +1 more source
Effects of dalcetrapib in patients with a recent acute coronary syndrome [PDF]
, 2012 In observational analyses, higher levels of high-density lipoprotein (HDL) cholesterol have been associated with a lower risk of coronary heart disease events.
Abt, Markus +18 more
core +2 more sources
High expression of antioxidant proteins in dendritic cells: possible implications in atherosclerosis [PDF]
Mol Cell Proteomics 5 (04/2006) 726-36, 2006 Dendritic cells (DCs) display the unique ability to activate naive T cells and to initiate primary T cell responses revealed in DC-T cell alloreactions. DCs frequently operate under stress conditions. Oxidative stress enhances the production of inflammatory cytokines by DCs.
arxiv +1 more source
The High Density Lipoprotein Cholesterol Hypothesis Revisited
Indonesian Biomedical Journal, 2018 BACKGROUND: The strong inverse association of plasma levels of high-density lipoprotein cholesterol (HDL-C) with coronary heart disease (CHD) found in human epidemiological studies led to the development of the ‘HDL-C hypothesis’, which posits that ...
Anna Meiliana +2 more
doaj +1 more source
Atherogenic Index of Plasma an Indicator for Predicting Cardiovascular Risk in Addition to Endothelial Dysfunction in Type 2 Diabetic Subjects [PDF]
Journal of Clinical and Diagnostic Research, 2018 Introduction: Prevalence of Cardiovascular Disease (CVD) in diabetic subjects is higher than that in the general population. Dyslipidaemia is a known atherogenic factor which causes vascular complications in both general and diabetic population ...
Siva Prasad Palem, Philips Abraham
doaj +1 more source
Re-examining the high-density lipoprotein hypothesis [PDF]
, 2016 published_or_final_versio
Tan, KCB
core +1 more source
A new lipid-structured model to investigate the opposing effects of LDL and HDL on atherosclerotic plaque macrophages [PDF]
arXiv, 2022 Atherosclerotic plaques form in artery walls due to a chronic inflammatory response driven by lipid accumulation. A key component of the inflammatory response is the interaction between monocyte-derived macrophages and extracellular lipid. Although concentrations of low-density lipoprotein (LDL) and high-density lipoprotein (HDL) particles in the blood
arxiv
Geometric and Electromagnetic Aspects of Fusion Pore Making [PDF]
Systems Biology 2 (2011), pp. 505-538, 2009 For regulated exocytosis, we model the morphology and dynamics of the making of the fusion pore or porosome as a cup-shaped lipoprotein structure (a dimple or pit) on the cytosol side of the plasma membrane. We describe the forming of the dimple by a free boundary problem.
arxiv +1 more source
Nanobiotechnology applications of reconstituted high density lipoprotein
Journal of Nanobiotechnology, 2010 High-density lipoprotein (HDL) plays a fundamental role in the Reverse Cholesterol Transport pathway. Prior to maturation, nascent HDL exist as disk-shaped phospholipid bilayers whose perimeter is stabilized by amphipathic apolipoproteins.
Ryan Robert O
doaj +1 more source