Results 51 to 60 of about 1,615,031 (256)

High density lipoprotein metabolism in low density lipoprotein receptor-deficient mice1[S]

open access: yesJournal of Lipid Research, 2014
The LDL receptor (LDLR) and scavenger receptor class B type I (SR-BI) play physiological roles in LDL and HDL metabolism in vivo. In this study, we explored HDL metabolism in LDLR-deficient mice in comparison with WT littermates.
Franz Rinninger   +6 more
doaj  

High density lipoproteins and exercise. [PDF]

open access: yesBritish Journal of Sports Medicine, 1980
High density lipoprotein (HDL) and total cholesterol (TC) levels have been measured and their ratio compared in four groups of subjects - those with vascular disease, controls, middle-aged "keep-fit" enthusiasts and young physical education students. Each group has also been subjected to analysis of risk factors known for atherosclerosis. The HDL level
D. R. Donaldson, R. C. Kester
openaire   +2 more sources

A Statin-Loaded Reconstituted High-Density Lipoprotein Nanoparticle Inhibits Atherosclerotic Plaque Inflammation

open access: yesNature Communications, 2014
Inflammation is a key feature of atherosclerosis and a target for therapy. Statins have potent anti-inflammatory properties but these cannot be fully exploited with oral statin therapy due to low systemic bioavailability.
R. Duivenvoorden   +21 more
semanticscholar   +1 more source

Recombinant high-density lipoprotein nanoparticles containing gadolinium-labeled cholesterol for morphologic and functional magnetic resonance imaging of the liver

open access: yesInternational Journal of Nanomedicine, 2012
Mengjie Rui,1 Wei Guo,2 Qian Ding,2 Xiaohui Wei,2 Jianrong Xu,3 Yuhong Xu21School of Life Science and Biotechnology, 2School of Pharmacy, Shanghai Jiao Tong University, Shanghai, People's Republic of China; 3Department of Radiology, Renji ...
Rui M, Guo W, Ding Q, Wei X, Xu J, Xu Y
doaj  

High-density lipoprotein: vascular protective effects, dysfunction, and potential as therapeutic target.

open access: yesCirculation Research, 2014
High-density lipoprotein (HDL) is a complex mixture of lipoproteins that is associated with many minor proteins and lipids that influence the function of HDL.
Thomas F. Lüscher   +3 more
semanticscholar   +1 more source

High Density Lipoprotein and it's Dysfunction [PDF]

open access: yesThe Open Biochemistry Journal, 2012
Plasma high-density lipoprotein cholesterol(HDL-C) levels do not predict functionality and composition of high-density lipoprotein(HDL). Traditionally, keeping levels of low-density lipoprotein cholesterol(LDL-C) down and HDL-C up have been the goal of patients to prevent atherosclerosis that can lead to coronary vascular disease(CVD).
Esin Eren, Necat Yilmaz, Ozgur Aydin
openaire   +3 more sources

High-density lipoprotein as a modulator of platelet and coagulation responses.

open access: yesCardiovascular Research, 2014
Platelets and coagulation factors are involved in the process of haemostasis, which ensures undisturbed blood flow upon vessel wall damage. However, excessive platelet aggregation and/or coagulation may lead to arterial or venous thrombosis.
Marco van der Stoep   +2 more
semanticscholar   +1 more source

MicroRNA control of high-density lipoprotein metabolism and function.

open access: yesCirculation Research, 2014
Recent discoveries of microRNAs (miRNAs) that control high-density lipoprotein abundance and function have expanded our knowledge of the mechanisms regulating this important lipoprotein subclass.
K. Rayner, K. Moore
semanticscholar   +1 more source

Beyond HDL-cholesterol increase: phospholipid enrichment and shift from HDL3 to HDL2 in alcohol consumers

open access: yesJournal of Lipid Research, 2007
The reduction of cardiovascular mortality associated with moderate alcohol consumption is chiefly thought to be mediated by an increase of high density lipoprotein cholesterol (HDL-CH).
Christian Schäfer   +6 more
doaj  

High-density lipoprotein, beta cells, and diabetes .

open access: yesCardiovascular Research, 2014
High-density lipoproteins (HDLs) exert a series of potentially beneficial effects on many cell types including anti-atherogenic actions on the endothelium and macrophage foam cells. HDLs may also exert anti-diabetogenic functions on the beta cells of the
A. von Eckardstein, C. Widmann
semanticscholar   +1 more source

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