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High Density Lipoprotein-Binding Proteins in Liver [PDF]
In one of the oldest civilizations we know, that of ancient Egypt, thoughts about the heart reflected a certain duality. On the one hand, the heart was associated with concepts like virtue, or soul.
Crom, M.P.G. (Rini) de
core
Stability of discoidal high-density lipoprotein particles [PDF]
Motivated by experimental and numerical studies revealing that discoidal high-density lipoprotein (HDL) particles may adopt flat elliptical and nonplanar saddle-like configurations, it is hypothesized that these might represent stabilized configurations of initially unstable flat circular particles. A variational description is developed to explore the
arxiv
Prevention of low density lipoprotein aggregation by high density lipoprotein or apolipoprotein A-I.
We have shown previously that low density lipoprotein (LDL) subjected to vortexing forms self-aggregates that are avidly phagocytosed by macrophages. That phagocytic uptake is mediated by the LDL receptor.
JC Khoo+3 more
doaj
Lipoprotein particles in patients with pediatric Cushing disease and possible cardiovascular risks. [PDF]
BackgroundCardiovascular (CV) complications are the most significant cause of mortality in adults with Cushing disease (CD); little is known about CV risk factors in children with CD.
Belyavskaya, Elena+10 more
core
The Association Between Cardiovascular Risk and Elevated Triglycerides [PDF]
BACKGROUND: The association between elevated triglycerides and cardiovascular risk has been extensively studied. The elevated level of triglycerides occurs through abnormalities in hepatic very low-density lipoprotein (VLDL) production and intestinal ...
Handayani, O. (Olivia)+1 more
core +3 more sources
Phospholipid transfer protein (PLTP), hepatic lipase (HL), and lipoprotein lipase (LPL) have all been reported to be intricately involved in HDL metabolism but the effect of PLTP on the apolipoprotein B-containing lipoproteins relative to that of HL and ...
Susan J. Murdoch+4 more
doaj
High-density lipoprotein, beta cells, and diabetes [PDF]
High-density lipoproteins (HDLs) exert a series of potentially beneficial effects on many cell types including anti-atherogenic actions on the endothelium and macrophage foam cells. HDLs may also exert anti-diabetogenic functions on the beta cells of the
von Eckardstein, Arnold+1 more
core
Maternal obesity is associated with the formation of small dense LDL and hypoadiponectinemia in the third trimester [PDF]
Context: Maternal obesity is associated with high plasma triglyceride, poor vascular function, and an increased risk for pregnancy complications. In normal-weight pregnant women, higher triglyceride is associated with increased small, dense low-density ...
Brown, E.A.+9 more
core +2 more sources
Pathways-driven Sparse Regression Identifies Pathways and Genes Associated with High-density Lipoprotein Cholesterol in Two Asian Cohorts [PDF]
Standard approaches to analysing data in genome-wide association studies (GWAS) ignore any potential functional relationships between genetic markers. In contrast gene pathways analysis uses prior information on functional structure within the genome to identify pathways associated with a trait of interest. In a second step, important single nucleotide
arxiv
Apolipoprotein M (apoM) is a novel apolipoprotein that is reportedly necessary for preβ HDL formation; however, its detailed function remains unknown. We investigated the biogenesis and properties of apoM and its effects on the initial steps of nascent ...
Anny Mulya+6 more
doaj