Results 91 to 100 of about 1,655,298 (265)

Evaluation of doses to pelvic lymph node regions from image-guided high-dose-rate interstitial brachytherapy for carcinoma of the uterine cervix

Journal of Contemporary Brachytherapy, 2023
Ajeet Gandhi, Madhup Rastogi, Vachaspati Kumar Mishra, Anoop Kumar Srivastava, Farhana Khatoon, Daya Nand Sharma   +5 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Single-fraction high-dose-rate brachytherapy: a scoping review on outcomes and toxicities for all disease sites

Journal of Contemporary Brachytherapy, 2022
Mehdi Kazemi, Sarah Nadarajan, Mitchell Kamrava   +2 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Low-dose-rate, high-dose-rate, and pulsed-dose-rate intra-cavitary brachytherapy for cervical cancer: The very first comparison study

Journal of Contemporary Brachytherapy
Daya Nand Sharma, Pavnesh Kumar, Vellaiyan Subramani, Prashanth Giridhar   +3 more
doaj   +1 more source

High-dose-rate brachytherapy as monotherapy for localized prostate cancer using three different doses – 14 years of single-centre experience

Journal of Contemporary Brachytherapy, 2020
Carlo Pietro Soatti, Durim Delishaj, Romerai D’Amico, Cristina Frigerio, Ilaria Costanza Fumagalli, Francesco Bonsignore, Giulia Sangalli, Fausto Declich, Stefano Arcangeli, Antonio Ardizzoia, Alessandro Colombo   +10 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Gold Nanoparticle Radiosensitization for High-Dose-Rate Brachytherapy: Differential Efficacy of PEG- and RGD-Functionalized Gold Nanoparticles Across 2-Dimensional, 3-Dimensional, and in vivo Prostate Cancer Models

International Journal of Nanomedicine
Daniel Cecchi,1 Nolan Jackson,1 Dmitri Karaman,2,3 Wayne Beckham,1 Chris D Johnstone,4 Samantha AM Lloyd,4,5 Devika Chithrani1,6,7 1Department of Physics and Astronomy, University of Victoria, Victoria, BC, Canada; 2Department of Mechanical Engineering ...
Cecchi D, Jackson N, Karaman D, Beckham W, Johnstone CD, Lloyd SA, Chithrani D   +6 more
doaj  

Editorial: Principles and Clinical Applications of Interstitial Brachytherapy

Frontiers in Oncology, 2022
Alexis Vrachimis, Alexis Vrachimis
doaj   +1 more source