Results 181 to 190 of about 1,655,298 (265)

Retrospective analysis of high-dose-rate brachytherapy for patients with prostate cancer aged ≥ 75 years. [PDF]

BMC Cancer
Matsuda K, Ogata T, Kamitani N, Watanabe K, Tokiya R, Hayashi T, Miyaji Y, Komura K, Tamada T, Katsui K.   +9 more
europepmc   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

An assessment of skill erosion on high-dose rate brachytherapy treatment planning. [PDF]

J Appl Clin Med Phys
DiCostanzo DJ, Allen TT, Ayan AS, Quick A, Evans KD, Patterson ES.   +5 more
europepmc   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Biological effects of conventional and ultra high dose rate radiation in human cells. [PDF]

Sci Rep
Ryan TL, Escalona MB, O'Brien K, Tan Y, Kanagaraj K, Taveras M, Nemzow L, Phillippi M, Deoli N, Wang E, Shuryak I, Garty G, Turner HC, Balajee AS.   +13 more
europepmc   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Automated EQD₂ reporting for cervical cancer high-dose-rate brachytherapy using a standalone ESAPI-based application. [PDF]

J Contemp Brachytherapy
Pavičar B, Kukić D, Milosavljević A, Sovilj BK, Janjić P, Milaković M, Tovilović M, Jaroš D, Predojević B.   +8 more
europepmc   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source