Results 181 to 190 of about 896,517 (311)

Estrogen Reduced Blood Glucose in High Fat-Fed Mice: An Animal Model of Type 2 Diabetes

open access: yesSiriraj Medical Journal, 2007
Objective: This study aims to produce a mouse model of type 2 diabetes by using high fat diet. The C57BL/6J mouse strain can develop type 2 diabetes by putting on high fat diet. Methods: A group of C57BL/6J male mice were fed with a high fat diet (53%
Suwattanee Kooptiwut   +2 more
doaj  

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

open access: yesAdvanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi   +10 more
wiley   +1 more source

Changes in serum cholinesterase (EC 3 1 * 1 * 8) activity in rats consuming a high-fat diet [PDF]

open access: bronze, 1989
Jesús Osada   +4 more
openalex   +1 more source

High-Fat Diet Alters Behavior and Hippocampal Gene Expression. [PDF]

open access: yesInt J Mol Sci
Totten MS   +3 more
europepmc   +1 more source

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