Results 201 to 210 of about 926,705 (358)

Effectiveness of Multivitamins vs Folic Acid on Prevention of Neural Tube Defects in Mouse Genetic Models and Human Organoids

Advanced Science, EarlyView.
Folic acid (FA) and multivitamins/minerals (MVM) are recommended for the prevention of neural tube defects (NTDs). Using a novel human neural tube‐like organoid system and mouse models, the study compares the effectiveness of two supplements on NTDs and cellular behaviors.
Huili Li, Jing Zhang, Lori Bulwith, Lee Niswander   +3 more
wiley   +1 more source

High‑fat diet and cognitive dysfunction: Mechanistic insights into diet‑induced neurodegeneration (Review). [PDF]

Int J Mol Med
You M, Wu F, Xiong F, Hu XF, Wu H, Zhou L, Zhang HX.   +6 more
europepmc   +1 more source

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

Advanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan, Ke‐Fan Li, Yi‐Ming Yuan, Man‐Cheng Xia, Fang‐Zhou Zhao, Hong‐Gang Ying, Zhuo Zhou, Peng‐Chao Gao, Guo‐Qing Xie, Xue‐Song Li, Hui Jiang, Rui‐Li Guan   +11 more
wiley   +1 more source

Microglial Feimin Alleviates Cognitive Impairment in High-Fat Diet-Fed Mice. [PDF]

Adv Sci (Weinh)
Gao R, Xiong Z, Su W, Deng J, Zhai B, Zhu G, Zhang M, Zeng Q, Qiu J, Bian Z, Xiao H, Luan G, Wang R.   +12 more
europepmc   +1 more source

Transient expression of factor VIII and a chronic high-fat diet induces ER stress and late hepatocyte oncogenesis

, 2022
Glenn F. Pierce, Aras N. Mattis
openalex   +2 more sources

Fermented Lacticaseibacillus Paracasei Cultures Ameliorate Colitis by Modulating Microbiota‐Derived Tryptophan Metabolism and Macrophage Polarization

Advanced Science, EarlyView.
A solid‐state fermented probiotic (PYW) is developed using wheat bran as substrate, containing high viable Lacticaseibacillus paracasei and bioactive metabolites. PYW alleviates intestinal inflammation by gut microbiota composition, enriching indole derivatives, activating aryl hydrocarbon receptor signaling, and regulating macrophage polarization. PYW
Heng Zhang, Jingzhou Sun, Xin Zheng, Huiqing Yang, Aowen Xie, Yuxuan Ding, Yuxia Mei, Jinshan Li, Yuanliang Hu, Min Ren, Yangyang Liu, Yunxiang Liang   +11 more
wiley   +1 more source

High-Fat Diet Alters Behavior and Hippocampal Gene Expression. [PDF]

Int J Mol Sci
Totten MS, Peterson AL, Pierce DM, Erikson KM.   +3 more
europepmc   +1 more source

A Natural Sweetener‐inducible Genetic Switch Controls Therapeutic Protein Expression in Mammals

Advanced Science, EarlyView.
This study develops a natural sweetener, the psicose‐inducible transgene expression (PURE) system based on an Agrobacterium tumefaciens–derived transcriptional repressor PsiR. The PURE system is highly specific to psicose, being insensitive to other sugars and structurally similar molecules.
Longliang Qiao, Zhihao Wang, Shasha Tang, Yuan Fang, Guiling Yu, Xiaoting Qiu, Lingxue Niu, Tao Yan, Xingwan Liu, Xiaoding Ma, Deqiang Kong, Yang Zhou, Ningzi Guan, Jinzhong Tian, Meiyan Wang, Haifeng Ye, Fengfeng Cai   +16 more
wiley   +1 more source

Transcriptomic Analysis of High-Intensity Interval Training in High-Fat-Diet-Induced Spontaneous Hypertensive Rats' Brains. [PDF]

Int J Mol Sci
Sadiq A, Shah IA, Wu BT, Lin YY, Su YA, Yang AL, Lee SD.   +6 more
europepmc   +1 more source

Cafeteria Diet Is a Robust Model of Human Metabolic Syndrome With Liver and Adipose Inflammation: Comparison to High-Fat Diet

, 2020
Brante P. Sampey, Amanda M. Vanhoose, Helena M. Winfield, Alex J. Freemerman, Michael J. Muehlbauer, Patrick T. Fueger, Christopher B. Newgard, Liza Makowski   +7 more
openalex   +1 more source