Results 261 to 270 of about 926,705 (358)

<i>Lacticaseibacillus rhamnosus</i> CU262 Attenuates High-Fat Diet-Induced Obesity via Gut-Liver Axis Reprogramming. [PDF]

Foods
Guo H, Pan L, Wang L, Huang Z, Wu Q, Wang J, Liao Z.   +6 more
europepmc   +1 more source

Impact of high-fat diet containing canola or soybean oil in the development of adiposity and bone struture

, 2012
Carlos Eduardo de Carvalho Costa
openalex   +1 more source

Anti-Obesity Effects of Pleurotus ferulae Water Extract on 3T3-L1 Adipocytes and High-Fat-Diet-Induced Obese Mice

Seulmin Hong, Seon Kyeong Park, Jangho Lee, Soo‐Hyun Park, Jae‐Ho Park, Yu Geon Lee   +5 more
openalex   +1 more source

The impact of high-fat, obesogenic diets on brain volume in a commercially available mouse model of fatty liver disease [PDF]

Li Jiang, Salaheldeen Elsaid, Cindy Zhan, Xin Li, Su Xu, Sui Seng Tee   +5 more
openalex   +1 more source

F13A1‐Mediated Macrophage Activation Promotes MASH Progression via the PKM2/HIF1A Pathway

Advanced Science, EarlyView.
In fatty liver disease, hepatocytes exposed to palmitate release S1P, which activates calcium signaling in macrophages. Elevated calcium enhances the activity of F13A1, driving PKM2 dimerization. The PKM2 dimers cause Warburg effect, translocate to the nucleus, cooperate with HIF1A, and upregulate IL1B expression, ultimately promoting classical ...
Qianrang Lu, Meiching Ong, Xuewen Yi, Muqiong Xing, Xinyao Tian, Ke Zhang, Ling Lu, Hao Wang, Xiaohan Lin, Jun Fang, Aibo Mu, Jiaying Cao, Jingyu Jiang, Feng Gao, Hongjun Li, Baohong Wang, Qi Ling   +16 more
wiley   +1 more source

The Influence of Strain and Sex on High Fat Diet-Associated Alterations of Dopamine Neurochemistry in Mice [PDF]

Kristen A. Hagarty-Waite, Heather A. Emmons, Steve C. Fordahl, Keith M. Erikson   +3 more
openalex   +1 more source

Leucine‐Dependent SLC7A5–PGAM5 Interaction Promotes Advanced Atherosclerosis Through Hindering Mitochondrial Function of Macrophages

Advanced Science, EarlyView.
Higher plasma leucine is associated with increased risk of new‐onset myocardial infarction. Leucine deprivation alleviates advanced atherosclerosis in mice. Tumor‐induced leucine deprivation reprograms macrophage metabolism and increases CD5Lhi macrophages in mouse plaques. Mechanistically, leucine deficiency reduced SLC7A5‐PGAM5 binding in macrophages,
Shan Zhong, Xueyu Wang, Qingsong Li, Siqi Wang, Bin Sun, Wenjun Ni, Gengyu Zhou, Fan Wang, Xianwei Xie, Cheng Jin, Gang Xu, Peng Zhao, Xiang Peng, Feiyuan Han, Xiangwen Xi, Yidan Wang, Juan Xu, Yue Wang, Xia Gu, Shuo Li, Jian Zhang, Shuijie Li, Jinwei Tian   +22 more
wiley   +1 more source

High-fat diet-induced obesity accelerates puberty in male rats through SMIM20/phoenixin upregulation. [PDF]

Front Endocrinol (Lausanne)
Xie T, Qin W, Zeng D, Wang R, Chen S, Chen Y, Zhong J, Lan D.   +7 more
europepmc   +1 more source

Polystyrene Microplastics Exposure Aggravates Clear Cell Renal Cell Carcinoma Progression via the NF‐κB and TGF‐β Signaling Pathways

Advanced Science, EarlyView.
This research provides the first comprehensive evidence that PS‐MPs exacerbate ccRCC progression by activating the NF‐κB and TGF‐β pathways. These findings establish PS‐MPs as an environmental risk factor for ccRCC progression and identify the NF‐κB and TGF‐β signaling as potential therapeutic targets to mitigate the adverse effects of ‐PS‐MPs exposure.
Shiqi Ye, Jianfeng Xiang, Siqi Zhou, Qintao Ge, Aihetaimujiang Anwaier, Kun Chang, Gang Wei, Jiahe Lu, Xi Tian, Shuxuan Zhu, Yuchen Jiang, Wei Zhang, Tingting Cai, Moran Xu, Dingwei Ye, Danfeng Xu, Tao Wang, Hailiang Zhang, Wenhao Xu   +18 more
wiley   +1 more source