Results 121 to 130 of about 28,492 (307)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Ghost-Free HDR Imaging in Dynamic Scenes via High–Low-Frequency Decomposition

Sensors
Generating high-quality high-dynamic-range (HDR) images in dynamic scenes remains a challenging task. Recently, Transformers have been introduced into HDR imaging and have demonstrated superior performance over traditional convolutional neural networks ...
Xiang Zhang, Genggeng Chen, Fan Zhang, Yongzhong Zhang   +3 more
doaj   +1 more source

Experimental investigation into the propagation of partial discharge pulses in transformers [PDF]

, 2002
An experimental investigation into the propagation behaviour of partial discharge (PD) pulses in a continuous disc type 6.6kV transformer winding is described in this paper.
Darwin, A., Crossley, P.A., Edwards, G., Hettiwatte, S.N., Wang, Z.D.   +4 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Field-Circuit Coupling Simulation and Application for Excitation Inductance in High-Frequency Transformers

Kongzhi Yu Xinxi Jishu
High-frequency transformers are a key component of power electronic transformer systems. To study excitation inductance in these transformers, this paper offers a novel qualitative analysis using the principle of iron-core reactors as a reference and ...
LI Gaolong, CHEN Li
doaj  

Selection of an Optimal Frequency for Offshore Wind Farms

Energies
Offshore wind power has attracted significant attention due to its high potential, capability for large-scale farms, and high capacity factor. However, it faces high investment costs and issues with subsea power transmission. Conventional high-voltage AC
Byeonghyeon An, Junsoo Che, Taehun Kim, Taesik Park   +3 more
doaj   +1 more source

Análise de transitórios elétricos em transformadores através do método TLM [PDF]

, 2003
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Elétrica.Este trabalho apresenta a aplicação eficiente do método numérico TLM- Transmission Line Method na solução dos principais ...
Cabral, Sérgio Henrique Lopes
core  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source