Results 61 to 70 of about 16,047,575 (289)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

High gain quad-port circularly polarized aperture-coupled MIMO antenna

Scientific Reports
This paper presents the design and implementation of a quad-port aperture-coupled circularly polarized (CP) multiple-input multiple-output (MIMO) antenna, specifically fitted for X-band applications.
Abdelhady M. Abdelhady, Hesham A. Mohamed, Wael A.E. Ali, Ahmed A. Ibrahim   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

SANTANA- Smart Antenna Terminal Design [PDF]

, 2005
This project is embedded in SANTANA (Smart Antenna Terminal) project. The project goal is to design a Ka-band circularly polarized antenna radiator for the receiver SANTANA system.
Liu, Ying, Ying, Liu
core  

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Evaluating the effect of antenna tilt and rotation on antenna performance in an indoor environment [PDF]

, 2011
In this paper the relative performances of antenna elements are assessed by combining the measured full (3D) far-field radiation patterns of each with measured angle of arrival data for a laboratory/office space.
Nix, AR, Geoffrey Hilton, Di Kong, Andrew Nix, David Halls, Mellios, E, Kong, D, Halls, DE, Evangelos Mellios, Hilton, GS   +9 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Antenna Gain Mismatch Calibration for Cooperative Base Stations

, 2011
In real environments, channel reciprocity cannot be directly exploited between uplink and downlink in time division duplex (TDD) due to antenna gain mismatch. Previous work about antenna calibration mainly focused on single cell.
Xiaodong Shen, Qixing Wang, Pan, Chengkang, Xiaodong, Shen, Wang, Qixing, Geng, Jian, Wei Xiang, Yang, Dacheng, Xiang, Wei, Guangyi, Liu, Jian Geng, Guangyi Liu, Chengkang Pan, Dacheng Yang, Fan Huang, Huang, Fan   +15 more
core   +1 more source

A Novel Methodology for Gain Enhancement of the Fabry-Pérot Antenna

IEEE Access, 2019
A significant problem that is encountered with the traditional Fabry-Pérot cavity (FPC) antenna is the nonuniform phase distribution inside the cavity, which adversely affects the radiation characteristics of the antenna.
Peng Xie, Guangming Wang, Haipeng Li, Xiangjun Gao   +3 more
doaj   +1 more source