Results 111 to 120 of about 11,295 (242)

MYC-driven increases in mitochondrial DNA copy number occur early and persist throughout prostatic cancer progression

JCI Insight, 2023
Increased mitochondrial function may render some cancers vulnerable to mitochondrial inhibitors. Since mitochondrial function is regulated partly by mitochondrial DNA copy number (mtDNAcn), accurate measurements of mtDNAcn could help reveal which cancers
Jiayu Chen, Qizhi Zheng, Jessica L. Hicks, Levent Trabzonlu, Busra Ozbek, Tracy Jones, Ajay M. Vaghasia, Tatianna C. Larman, Rulin Wang, Mark C. Markowski, Sam R. Denmeade, Kenneth J. Pienta, Ralph H. Hruban, Emmanuel S. Antonarakis, Anuj Gupta, Chi V. Dang, Srinivasan Yegnasubramanian, Angelo M. De Marzo   +17 more
doaj   +1 more source

Clinically Significant Prostate Cancer in Men With High-Grade Intraepithelial Prostatic Intraepithelial Neoplasia or Atypical Small Acinar Proliferation

, 2023
Robert D. Norman, Harshit Garg, Lanette Rickborn, Dharam Kaushik, Deepak Pruthi, Ahmed M. Mansour, Ian M. Thompson, Michael A. Liss   +7 more
openalex   +1 more source

Glyoxalase 1 Expression as a Novel Diagnostic Marker of High-Grade Prostatic Intraepithelial Neoplasia in Prostate Cancer. [PDF]

Cancers (Basel), 2021
Rounds L, Nagle RB, Muranyi A, Jandova J, Gill S, Vela E, Wondrak GT.   +6 more
europepmc   +1 more source

Roles of tumor suppressors in regulating tumor-associated inflammation. [PDF]

, 2014
Loss or silencing of tumor suppressors (TSs) promotes neoplastic transformation and malignant progression. To date, most work on TS has focused on their cell autonomous effects.
Karin, M, Yang, L
core   +1 more source

Vascular endothelial growth factor (VEGF) and prostate pathology

International Brazilian Journal of Urology, 2010
PURPOSE: Previous studies suggest that vascular endothelial growth factor (VEGF) circulating levels might improve identification of patients with prostate cancer but results are conflicting.
Francisco Botelho, Francisco Pina, Pedro Silva, Gabriela Figueiredo, Francisco Cruz, Nuno Lunet   +5 more
doaj   +1 more source

Conditional Expression of Human 15-Lipoxygenase-1 in Mouse Prostate Induces Prostatic Intraepithelial Neoplasia: The FLiMP Mouse Model

Neoplasia: An International Journal for Oncology Research, 2006
The incidence and mortality of prostate cancer (PCa) vary greatly in different geographic regions, for which lifestyle factors, such as dietary fat intake, have been implicated.
Uddhav P. Kelavkar, Anil V. Parwani, Scott B. Shappell, W. David Martin   +3 more
doaj   +1 more source

The molecular and cellular origin of human prostate cancer [PDF]

, 2016
Prostate cancer is the most commonly diagnosed male malignancy. Despite compelling epidemiology, there are no definitive aetiological clues linking development to frequency.
Abate-Shen, Abrahamsson, Adler, Al-Hajj, Albini, Ammirante, An, An, Anderson, Anderson, Antonarakis, Ao, Armitage, Baca, Baker, Bapat, Barbieri, Barker, Barsky, Beck, Beltran, Ben-Neriah, Bergh, Bernstein, Berry, Bethel, Birkeland, Birnie, Blackwood, Bonnet, Borel, Bostwick, Bostwick, Boysen, Briganti, Bubendorf, Burkhardt, Caini, Cairns, Calabrese, Cancer Research UK, Carreira, Cesare, Chakkalakal, Chapman-Rothe, Chen, Cheshier, Choi, Chua, Clevers, Cloos, Cohen, Cohen, Collins, Collins, Conboy, Cooper, Culig, Culig, Cunha, Cunha, Dan Robinson, Das, Dawson, De Marzo, De Marzo, Dehm, Deng, Dermer, Ding, Don-Doncow, Donaldson, Dong, Ebelt, Eggener, Eminaga, Epstein, Eramo, Essers, Fang, Fassi Fehri, Fearon, Feinberg, Feng, Fialkow, Figueiredo, Foudi, Frame, Frame, Frame, Franco, Franks, Gan, Gannon, Gao, Gendrel, Gerlinger, Germann, Ghajar, Gibbs, Gimelbrant, Gleason, Gleave, Goardon, Goldstein, Gong, Goodwin, Gotay, Grasso, Grasso, Greaves, Grisanzio, Gundem, Guo, Gupta, Gurel, Guryanova, Gutierrez-Arcelus, Haapala, Haas, Haffner, Haffner, Haffner, Haffner, Hahn, Hall, Hall, Han, Hanahan, Hansel, He, Heaphy, Hecht, Heer, Herawi, Hermann, Hernandez, Heydt, Hjelmeland, Hong, Hong, Hovelson, Hrbacek, Hu, Huels, Huggins, Hurt, Hurt, Hägglöf, IACR, Iliopoulos, Iliou, Inaguma, Isaacs, Jafari, Jiao, Jin, John R. Packer, Johnston, Jones, Jones, Joseph, Karanika, Karantanos, Karthaus, Ke, Ke, Keller, Kelly, Kiel, Kim, Kooistra, Korpal, Kouzarides, Kovtun, Kreso, Krieger, Krieger, Kroon, Kulac, Kunderfranco, Lang, Lang, Lanie, Lapointe, Lark, Lavery, Lee, Lee, Leong, Leongamornlert, Li, Li, Li, Li, Lilja, Lin, Lin, Ling, Liu, Lo, Loeb, Luedeke, Lukacs, Ma, Mahmud, Maini, Maitland, Maitland, Maitland, Maitland, Mani, Marinov, Martin, Matsui, Meeker, Mehrotra, Menon, Merok, Metsalu, Metzger, Meyer, Michaud, Miyamoto, Mohan, Mounir, Munger, Nag, Nag, Nakai, Nakashima, Navarro, Nelson, Network, Nonn, Nonomura, Norman J. Maitland, Norrish, Nowell, O'Callaghan, O'Sullivan, Ohm, Olumi, Osman, Ousset, Park, Pascale, Patel, Patel, Patra, Patrawala, Patrawala, Pellacani, Penney, Perner, Perner, Perry, Peto, Pierce, Platz, Polson, Potten, Potter, Prince, Pritchard, Putzi, Qin, Rajan, Rando, Rane, Rane, Raval, Reik, Ricci-Vitiani, Ricci-Vitiani, Rich, Richardson, Riley, Risbridger, Robinson, Rodriguez, Rosa Mendoza, Ross-Adams, Roth, Ruska, Rutella, Sack, Sakr, Schiewer, Schober, Schroeder, Sfanos, Sfanos, Sfanos, Sfanos, Sharma, Sharma, Shen, Shibata, Shinohara, Shiozawa, Singh, Singh, Slaughter, Smith, Sneddon, Sommerfeld, Song, Song, Steinhauser, Stewart, Strand, Strasner, Stratton, Strickler, Sugimura, Suzuki, Tan, Tan, Tang, Taplin, Taylor, Tepper, Thompson, Ting, Ting, Toh, Tollervey, Tomasetti, Tomasetti, Tomasetti, Tomlins, Tomlins, Tomlinson, Tomlinson, Trock, True, Trumpp, Tuxhorn, Twillie, Urquidi, Ushijima, Valastyan, Van, Van Asperen, Vincent, Vindrieux, Visakorpi, Visvader, Vogelstein, Vral, Wang, Wang, Wang, Wang, Wang, Wang, Watt, Weinberger, Whitaker, Wild, Williams, Wilson, Woo, Wymenga, Xiang, Xiang, Xu, Yachida, Yamamoto, Yatabe, Yoshimoto, Yu, Zambrano, Zhang, Zhang, Zhang   +376 more
core   +1 more source

Immunohistochemical analysis of ezrin-radixin-moesin-binding phosphoprotein 50 in prostatic adenocarcinoma

BMC Urology, 2011
Background Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) is an adapter protein which has been shown to play an active role in a wide variety of cellular processes, including interactions with proteins related to both tumor suppression and ...
Chandran Uma R, Becich Michael J, Bartholow Tanner L, Parwani Anil V   +3 more
doaj   +1 more source

p53 Alteration and Chromosomal Instability in Prostatic High-Grade Intraepithelial Neoplasia and Concurrent Carcinoma: Analysis by Immunohistochemistry, Interphase In Situ Hybridization, and Sequencing of Laser-Captured Microdissected Specimens [PDF]

, 2001
Jaudah Al‐Maghrabi, Lada Vorobyova, William Chapman, Michael A.S. Jewett, Maria Zieleńska, Jeremy A. Squire   +5 more
openalex   +1 more source

Membrane-type matrix metalloproteinases: expression, roles in metastatic prostate cancer progression and opportunities for drug targeting [PDF]

, 2017
YesThe membrane-type matrix metalloproteinases (MT-MMPs), an important subgroup of the wider MMP family, demonstrate widespread expression in multiple tumor types, and play key roles in cancer growth, migration, invasion and metastasis. Despite a large
Falconer, Robert A., Loadman, Paul M.
core   +1 more source