Results 201 to 210 of about 11,295 (242)

Epidemology of High Grade Prostatic Intraepithelial Neoplasia

Pathology - Research and Practice, 1995
The prevalence of high grade prostatic intraepithelial neoplasia (HGPIN), the age at which this lesion starts and the potential racial or ethnic differences in its distribution are poorly documented. HGPIN is becoming increasingly implicated as a premalignant lesion for clinically significant prostatic carcinoma (PCa) with mounting evidence linking it ...
W A, Sakr, D J, Grignon, G P, Haas, K L, Schomer, L K, Heilbrun, B J, Cassin, J, Powell, J A, Montie, J E, Pontes, J D, Crissman   +9 more
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CDK19 as a diagnostic marker for high-grade prostatic intraepithelial neoplasia

Human Pathology, 2021
High-grade prostatic intraepithelial neoplasia (HGPIN) is a facultative precursor lesion of prostate cancer (PCa). Multifocal HGPIN in needle biopsies in the absence of PCa indicates a higher risk of cancer detection in subsequent biopsies. Therefore, a reliable diagnosis of HGPIN is of high clinical relevance guiding the management of patients with ...
Anne, Offermann, Vincent, Joerg, Marie C, Hupe, Finn, Becker, Marten, Müller, Johannes, Brägelmann, Jutta, Kirfel, Axel S, Merseburger, Verena, Sailer, Lars, Tharun, Sven, Perner   +10 more
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Significance of high-grade prostatic intraepithelial neoplasia on prostate biopsy

Urologic Oncology: Seminars and Original Investigations, 2003
The early diagnosis of prostate cancer has been facilitated by the development of serum prostate-specific antigen (PSA) testing and evolution in transrectal ultrasound-guided biopsy of the prostate. Over a decade has passed since the initial recommendations for systematic sextant sampling of the prostate to increase the accuracy of cancer detection ...
Maxwell V, Meng, Katsuto, Shinohara, Gary D, Grossfeld   +2 more
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Multilocular prostatic cystadenoma with high-grade prostatic intraepithelial neoplasia

Urology, 2003
Multilocular prostatic cystadenoma is a rarely encountered neoplasm located in the midline between the bladder and rectum that is either attached to the prostate by a pedicle or separate from the prostate entirely. Histologically and immunohistochemically these lesions resemble benign prostate tissue.
Elizabeth A, Allen, David A, Brinker, Domenico, Coppola, Jose I, Diaz, Jonathan I, Epstein   +4 more
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Architectural patterns of high-grade prostatic intraepithelial neoplasia

Human Pathology, 1993
High-grade prostatic intraepithelial neoplasia (PIN) is characterized by cellular proliferations within pre-existing ducts and glands with cytologic changes mimicking adenocarcinoma, including prominent nucleoli, but lacking stromal invasion. To determine the architectural spectrum of high-grade PIN, 60 serially sectioned radical prostatectomy ...
D G, Bostwick, M B, Amin, P, Dundore, W, Marsh, D S, Schultz   +4 more
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Foamy Gland High-Grade Prostatic Intraepithelial Neoplasia

The American Journal of Surgical Pathology, 2000
A 60-year-old man underwent radical prostatectomy for biopsy-proved adenocarcinoma of the prostate. Histologic examination of the entirely embedded prostatectomy specimen revealed extensive ordinary adenocarcinoma, Gleason's grade 3 + 3 = 6, involving both sides of the gland, and extending into extraprostatic soft tissue at the left base.
D M, Berman, J, Yang, J I, Epstein
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Shifting Paradigms for High-grade Prostatic Intraepithelial Neoplasia

European Urology, 2016
High-grade prostatic intraepithelial neoplasia (HGPIN) has long been considered a histologic precursor to invasive prostate adenocarcinoma (PCA), with the canonical view stating that HGPIN progresses unidirectionally to PCA. This notion is based on the observations that HGPIN lesions are often found in close proximity to PCA and share a large ...
Michael C, Haffner, Christopher E, Barbieri   +1 more
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High-Grade Prostatic Intraepithelial Neoplasia in Dogs

European Urology, 1999
The dog is the only nonhuman species in which high-grade intraepithelial neoplasia (HGPIN) and invasive carcinoma spontaneously occur. Our work was the first to describe HGPIN in the dog prostate. Canine HGPIN bears remarkable morphologic similarity to its human counterpart.
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High grade prostatic intraepithelial neoplasia is a disease

Current Urology Reports, 2001
High grade prostatic intraepithelial neoplasia (PIN) is now widely accepted as the main premalignant lesion that has the potential to progress to prostate adenocarcinoma. High grade PIN is a standard diagnosis that must be included as part of the reported pathologic evaluation of prostate biopsies.
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High-grade prostatic intraepithelial neoplasia: State-of-the-art

Arkhiv patologii, 2015
According to current views, high-grade prostatic intraepithelial neoplasia is the most likely precursor of prostate adenocarcinoma. This review gives the latest data of genetic, proteomic, and morphological analyses of this neoplasia and touches upon the probems that might arise when searching for new markers for differential diagnosis and prognosis ...
D O, Allina, Yu Yu, Andreeva, L E, Zavalishina, T V, Kekeeva, G A, Frank   +4 more
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