Results 211 to 220 of about 11,295 (242)
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Preneoplasia in the prostate gland with emphasis on high grade prostatic intraepithelial neoplasia
Pathology, 2013There are a variety of morphological patterns and processes that have been implicated in the pathogenesis of prostate cancer. Prostatic intraepithelial neoplasia (PIN), inflammation with or without atrophy, and adenosis (atypical adenomatous hyperplasia) have all been given candidate status as precursor lesions of prostatic adenocarcinoma.
Jennifer L O, Merrimen +2 more
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Unusual Histologic Types of High-Grade Prostatic Intraepithelial Neoplasia
The American Journal of Surgical Pathology, 1997High-grade prostatic intraepithelial neoplasia (HGPIN) is the most likely precursor proliferation of peripheral zone, moderately to poorly differentiated prostatic adenocarcinomas. The usual cell type of the epithelial lining of HGPIN is a glandular epithelial cell with characteristic nuclear abnormalities. Here we report nine cases of unusual types of
A O, Reyes +3 more
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The Incidence of High Grade Prostatic Intraepithelial Neoplasia in Needle Biopsies
Journal of Urology, 1995High grade prostatic intraepithelial neoplasia is the most likely precursor of invasive prostate cancer. The identification of prostatic intraepithelial neoplasia in needle biopsy specimens warrants repeat biopsy because of its high predictive value for cancer.
D G, Bostwick, J, Qian, K, Frankel
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Immunoreactive p53 Protein in High-Grade Prostatic Intraepithelial Neoplasia
Pathology - Research and Practice, 1995p53 protein accumulation in the nuclei of prostatic carcinoma cells, as detected by immunohistochemistry, has been associated with increased cell proliferation rate, increased histologic grade and stage, androgen independence and decreased patient survival.
P A, Humphrey, P E, Swanson
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High-Grade Prostatic Intraepithelial Neoplasia
2017High-grade prostatic intraepithelial neoplasia is the precursor lesion for prostatic acinar adenocarcinoma. While common spatial, epidemiological, histological and immunophenotypical features exist between high-grade prostatic intraepithelial neoplasia and adnocarcinoma, they also share different cytogenetic, mutational and molecular abnormalities ...
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High-grade prostatic intraepithelial neoplasia and prostate cancer risk reduction
World Journal of Urology, 2003High-grade prostatic intraepithelial neoplasia (PIN) is the earliest accepted stage in carcinogenesis, possessing most of the phenotypic and biochemical changes in cancer without invasion of the basal membrane of the acini. The support for high-grade PIN as the main premalignant lesion of prostate cancer is based on several lines of evidence derived ...
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Central zone histology of the prostate: A mimicker of high-grade prostatic intraepithelial neoplasia
Human Pathology, 2002The central zone (CZ) is located at the base of the prostate adjacent to the seminal vesicles. Its histology as a potential mimicker of high-grade prostatic intraepithelial neoplasia (PIN) has not been formally studied. Three groups were evaluated. Group 1 comprised 30 consecutive radical prostatectomy specimens assessed for the extent of CZ and of ...
Monica, Srodon, Jonathan I, Epstein
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European Urology, 2012
a Section of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, Italy; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA; Department of Pathology, Reina Sofia University Hospital and Faculty of Medicine, Cordoba, Spain; Department ...
Montironi R. +5 more
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a Section of Pathological Anatomy, Polytechnic University of the Marche Region, School of Medicine, United Hospitals, Ancona, Italy; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN, USA; Department of Pathology, Reina Sofia University Hospital and Faculty of Medicine, Cordoba, Spain; Department ...
Montironi R. +5 more
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Actas Urológicas Españolas (English Edition), 2014
High grade prostatic intraepithelial neoplasia (HGPIN) is regarded as a precursor of prostate cancer (PC). However, its relationship to cancer has changed throughout the literature, being currently poorly defined and remains controversial for urologists in their clinical practice.
J, Bastarós +4 more
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High grade prostatic intraepithelial neoplasia (HGPIN) is regarded as a precursor of prostate cancer (PC). However, its relationship to cancer has changed throughout the literature, being currently poorly defined and remains controversial for urologists in their clinical practice.
J, Bastarós +4 more
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Ductal Spread Versus High-Grade Prostatic Intraepithelial Neoplasia
International Journal of Surgical Pathology, 2016Ductal spread (DS) of acinar adenocarcinoma of the prostate can lead to an incomplete replacement of the benign epithelium by cancer cells, resulting in a lesion that can be indistinguishable from high-grade prostatic intraepithelial neoplasia (HGPIN).
Andres M, Acosta +3 more
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