European Journal of Histochemistry, 2009 The antigen Ki-67, which is associated with cell proliferation, has been demonstrated to be useful in predicting the development of human tumors. The objective of this study was to evaluate the prognostic utility of this biomarker in pre-malignant and ...
E Muñoz, F Gómez, JI Paz, I Casado
doaj +1 more source
KI-67 IMMUNOHISTOHEMICAL EXPRESSION IN PROSTATIC LESIONS
The Iraqi Journal of Medical Sciences, 2017 Background: The cell proliferation marker, ki-67, is a nuclear and nucleolar protein, which can be detected during all active phases of the cell cycle (G1, S, G2, and mitosis), but absent from cell resting phases.
Inas A. Rasheed +2 more
doaj +6 more sources
Translationally controlled tumor protein in prostatic adenocarcinoma: correlation with tumor grading and treatment-related changes [PDF]
, 2015 12Prostate cancer is the second leading cause of cancer-related death. The androgen deprivation therapy is the standard treatment for advanced stages. Unfortunately, virtually all tumors become resistant to androgen withdrawal.
Alessandro Ginori +11 more
core +11 more sources
Basal cell markers:34BE12 and p63, improving detection of basal cells in atypical prostatic lesions
مجله كليه طب الكندي, 2019 Background: The diagnosis of prostatic pathology may be of challenging , as some difficult and suspected, atypical cases may lack basal cell layer by routine H&E sections . Antibodies against 34BE12(HMW-CK) and p63 aid the diagnosis of such cases ,
Inas A. Rasheed
doaj +1 more source
Predicting prostate biopsy outcome: Prostate health index (phi) and prostate cancer antigen 3 (PCA3) are useful biomarkers [PDF]
, 2012 Indication for prostate biopsy is presently mainly based on prostate-specific antigen (PSA) serum levels and digital-rectal examination (DRE). In view of the unsatisfactory accuracy of these two diagnostic exams, research has focused on novel markers to ...
A. D. Carlo +13 more
core +1 more source
Pathogenic Intestinal Bacteria Enhance Prostate Cancer Development via Systemic Activation of Immune Cells in Mice [PDF]
, 2013 A role for microbes has been suspected in prostate cancer but difficult to confirm in human patients. We show here that a gastrointestinal (GI) tract bacterial infection is sufficient to enhance prostate intraepithelial neoplasia (PIN) and microinvasive ...
A Peled +43 more
core +13 more sources
Diagnostic utility of α-methylacyl CoA racemase (P504S) & HMWCK in morphologically difficult prostate cancer [PDF]
, 2010 Background To evaluate the diagnostic utility of alpha-methylacyl CoA racemase (P504S) & HMWCK (34beta E12) in morphologically difficult prostate cancer.
K Kumaresan +5 more
core +1 more source
Health Science Journal of Indonesia, 2020 Latar Belakang: Gangguan regulasi mikroRNA(miR) dan inflamasi kronik dapat mengubah tumor menjadi karsinoma dan kanker dengan metastasis melalui perubahan seluler dan genomik. Lesi prekanker memiliki peluang 33,3 persen menjadi kanker.
Rachma Greta Putri +6 more
doaj +1 more source
Tailored for Real-World: A Whole Slide Image Classification System Validated on Uncurated Multi-Site Data Emulating the Prospective Pathology Workload. [PDF]
, 2020 Standard of care diagnostic procedure for suspected skin cancer is microscopic examination of hematoxylin & eosin stained tissue by a pathologist. Areas of high inter-pathologist discordance and rising biopsy rates necessitate higher efficiency and ...
Ayyagari, Devi +11 more
core +1 more source
The use of immunohistochemistry for diagnosis of prostate cancer [PDF]
, 2010 PURPOSE: Atypical glands (ASAP) are diagnosed in 5.0% of prostate biopsies, and cancer identification in a rebiopsy is higher than 40.0%. The use of antibodies to mark basal cells is currently a common practice, in order to avoid rebiopsies.
ANTUNES, Alberto A. +7 more
core +2 more sources