Results 51 to 60 of about 11,295 (242)
Boolean analysis identifies CD38 as a biomarker of aggressive localized prostate cancer. [PDF]
, 2018 The introduction of serum Prostate Specific Antigen (PSA) testing nearly 30 years ago has been associated with a significant shift towards localized disease and decreased deaths due to prostate cancer.
Auman, Heidi +16 more
core +2 more sources
High Grade Prostatic Intraepithelial Neoplasia, Foamy Variant
, 2020 National Cancer Institute
openalex +2 more sources
ZEB1 is Negatively Correlated with E-Cadherin in Prostatic Anomaly Tissue
MCBS (Molecular and Cellular Biomedical Sciences), 2022 Background: Prostatic anomalies are common in tumor or infection condition. The enlargement of prostate gland affects the epithelial cell polarity that involves epithelial-mesenchymal transition (EMT).
Sari Eka Pratiwi +7 more
doaj +1 more source
Regulation of histone H2A.Z expression is mediated by sirtuin 1 in prostate cancer [PDF]
, 2013 Histone variants seem to play a major role in gene expression regulation. In prostate cancer, H2A.Z and its acetylated form are implicated in oncogenes’ upregulation.
Amado, Francisco +8 more
core +2 more sources
Urological Science, 2018 Objective: Atypical small acinar proliferation (ASAP) and high-grade prostatic intraepithelial neoplasia (HGPIN) are two pathological findings occasionally noted in prostate biopsies.
Sheng-Yung Tung +7 more
doaj +1 more source
Heat shock protein 90 is associated with hyperplasia and neoplastic transformation of canine prostatic epithelial cells [PDF]
, 2014 Heat shock protein 90 (HSP90) is a molecular chaperone that regulates critical signalling proteins of cancer development and progression. Abnormal levels of HSP90 have been observed in human prostatic carcinoma (PC), with prognostic and therapeutic ...
Benazzi, C. +3 more
core +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Autocrine regulation of human prostate carcinoma cell proliferation by somatostatin through the modulation of the SH2 domain containing protein tyrosine phosphatase (SHP)-1 [PDF]
, 2002 The present study was intended to gain additional information on the growth regulation of prostate by somatostatin\ud (SRIF) and the intracellular events involved.
Angulo, Javier +10 more
core +3 more sources
Advanced Science, EarlyView.This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu +18 more
wiley +1 more source
Advanced Science, EarlyView.ABSTRACT Blood‐based liquid biopsies hold transformative potential for non‐invasive cancer management, but current approaches relying on rare circulating tumor components limit their broad clinical utility. Platelets, abundant in blood and mediating diverse cancer‐associated responses, represent a compelling yet largely unexplored alternative.
Yan Ma +28 more
wiley +1 more source