Results 121 to 130 of about 16,664 (252)
ABSTRACT High‐risk human papillomaviruses (HPV) are the main etiological agents of cervical cancer. The viral early promoter regulates the expression of E6/E7 oncoproteins, and its transcriptional activity is positively or negatively regulated by host transcription factors (TFs) that are able to bind to the viral long control region (LCR).
Valéria Talpe‐Nunes +11 more
wiley +1 more source
Objective: Cervical cancer is a major cause of cancer-related mortality, necessitating effective screening and diagnostic methods. This study aimed to assess the performance of cervicovaginal smear (CVS) and human papillomavirus (HPV)-DNA co-test.
Neslihan Kaya Terzi, Ozden Yulek
doaj +1 more source
Priscila Thaís Silva Mantoani,1,2 Douglas Côbo Micheli,2 Millena Prata Jammal,2 Julia Hailer Vieira,3 Márcia Antoniazi Michelin,3 Caroline Gabriela Xavier Ferreira,2 Henrique Nascimento Silva,2 Eddie Fernando Candido Murta,2 Rosekeila Simões Nomelini1,2 ...
Michelin MA +8 more
core
ABSTRACT Human papillomavirus (HPV) is the most common sexually transmitted infection worldwide and is responsible for anogenital warts and several cancers. Although the effectiveness of female HPV vaccination has been well established since its introduction in 2006, no systematic review has specifically evaluated the impact of male vaccination ...
Anna Beltrame +5 more
wiley +1 more source
About 9.4% of patients with biopsy‐proven high‐grade cervical lesions had ultimately no high‐grade lesion (HGIL) in the excision specimen. The probability of the absence of HGIL was significantly increased in patients with a small lesion, with minor changes or normal colposcopy, and in those with normal cytology or minor abnormalities.
Sophia Assirlikian +10 more
wiley +1 more source
We report a series of 12 patients (mean age 63 years) with chronic oesophageal ulceration showing morphological features of IgG4‐related inflammatory disease. Most patients underwent several rounds of endoscopy until this association was recognized. The majority of patients went into clinical and histological remission following corticosteroid therapy.
Hanna Henzinger +5 more
wiley +1 more source
What's new? Persistent infection with high‐risk human papillomavirus (HPV) causes most invasive cervical cancer cases, leading many countries to transition from cytology to primary HPV‐based screening. Despite the benefits, HPV‐based screening may also lead to unnecessary procedures, psychological burden, and strain on healthcare systems.
Kelsi R. Kroon +2 more
wiley +1 more source
PD-L1 Expression and Immune Response in Squamous Cervical Lesion and Squamous Cell Carcinoma Cervix
Aim : To explore the possibility of using anti-PD-L1 immunotherapy in low-grade intraepithelial lesion (LSIL), high-grade intraepithelial lesion (HSIL), and squamous cell carcinoma (SCC) of the cervix.
Syarifuddin Wahid +5 more
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What's new? Primary human papillomavirus (HPV)–based screening has shown superiority to cytology‐based screening in reducing cervical cancer risk in clinical trials. However, the benefit must be balanced with potential overdiagnosis/overtreatment.
Jeppe Bennekou Schroll +11 more
wiley +1 more source
BACKGROUND: The Bethesda System uses a two-tiered approach in the diagnosis of cervical squamous intraepithelial lesions (SILs). Occasionally, Papanicolaou (Pap) tests with evident low-grade SIL (LSIL) also have some features suggestive but not ...
Yee-Chang, Melissa +7 more
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