An elderly male patient with extramammary Paget disease of the scrotum and multiple metastases was treated with fractionated FLASH‐RT (40 Gy in 5 fractions) in the scrotal lesion. Abstract Objective Ultrahigh‐dose‐rate radiotherapy (FLASH‐RT) has been shown to reduce radiation‐induced normal tissue injury in preclinical studies.
Hui Luo +14 more
wiley +1 more source
Research of the Potential Vaginal Microbiome Biomarkers for High-Grade Squamous Intraepithelial Lesion. [PDF]
Chao X +6 more
europepmc +1 more source
SOX1/PAX1 Methylation for Triage of HPV‐Positive Women in Cervical Cancer Screening: A Cohort Study
ABSTRACT Objective To establish a better triage strategy using SOX1/PAX1 methylation detection for high‐risk HPV (hrHPV)‐positive women than cytology. Design A cohort study. Setting Population‐based cervical cancer (CC) screening cohort. Population A total of 5684 women were enrolled.
Hongyu Xie +6 more
wiley +1 more source
Background: Human papillomavirus (HPV) infection is the main risk factor for development of precancerous intraepithelial lesions and cervical cancer. However, not only HPV, but also HPV type, is a very important factor for malignant transformation. The
Nikolovski, Sotir +3 more
core +1 more source
The Plasma DIA-Based Quantitative Proteomics Reveals the Pathogenic Pathways and New Biomarkers in Cervical Cancer and High Grade Squamous Intraepithelial Lesion. [PDF]
Han S +9 more
europepmc +1 more source
ABSTRACT Background Vulval Lichen Sclerosus (VLS) is a chronic inflammatory condition requiring lifelong management to prevent severe complications including malignancy. A shared care model between general practitioners (GPs) and public non‐GP specialists (dermatologist or gynaecologist) for patients with stable LS would alleviate the demand on public ...
Arav Kannen +3 more
wiley +1 more source
Diabetes associated with cervical carcinoma among high-risk HPV-infected patients with cytologically diagnosed high grade squamous intraepithelial lesion. [PDF]
Yue C, Zhang C, Ying C, Jiang H.
europepmc +1 more source
Risk factors predicting residual lesion in subsequent hysterectomy following cold knife conization (CKC) for high-grade squamous intraepithelial lesion (HSIL). [PDF]
Zeng Y +7 more
europepmc +1 more source
Large‐scale HPV self‐sampling screening distributed 557 976 kits, resulting in 208 386 returned samples with 98% validity. HPV positivity was detected in 19% of participants, leading to clinical follow‐up. Biopsy confirmed 980 high‐grade cervical lesions and 32 cervical cancers.
Caroline Hellsten +2 more
wiley +1 more source
Diagnosis of penile cancer with ex vivo fluorescence confocal microscopy using the Histolog® Scanner
Objectives To evaluate the feasibility and diagnostic performance of ex vivo fluorescence confocal microscopy (FCM) using the Histolog® Scanner (SamanTree Medical SA, Lausanne, Switzerland) for the assessment of penile cancer (PeCa) specimens, and to compare FCM‐based diagnoses with standard formalin‐fixed, paraffin‐embedded (FFPE) histopathology ...
Xiaohu Zhang +8 more
wiley +1 more source

