Results 171 to 180 of about 834,651 (394)

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source

Isoleucine‐restricted diets improve high‐fat diet‐induced nonalcoholic fatty liver disease via regulating insulin resistance and gut microbiota

Food Frontiers
Obesity, caused V̇ by a long‐term high‐fat diet, is a risk factor for insulin resistance and nonalcoholic fatty liver disease (NAFLD). The gut microbiota plays an important role in NAFLD development by producing lipopolysaccharides (LPS). Isoleucine (ILE)
Xing Zhou, Rili Hao, Xiangyang Zhu, Xintong Tan, Dapeng Li   +4 more
doaj   +1 more source

The Effect of Simvastatin on Gut Microbiota and Lipid Metabolism in Hyperlipidemic Rats Induced by a High-Fat Diet [PDF]

, 2020
Qing Zhang, Xiaoyun Fan, Rui Ye, Yuzhong Hu, Tingting Zheng, Rui Shi, Wenjian Cheng, Xu‐Cong Lv, Lijiao Chen, Peng Liang   +9 more
openalex   +1 more source

Effects of breed type, silage harvest date and pattern of offering concentrates on intake, performance and carcass traits of finishing steers [PDF]

, 2007
peer-reviewedThe objective of this experiment was to investigate the effects and interactions of breed type, silage harvest date and pattern of offering concentrates on intake, performance and carcass traits of finishing steers.
Cummins, B., Keane, Michael G., Kenny, David A., O'Kiely, Padraig   +3 more
core  

Western Diet Inhibits FUT7‐Mediated Treg Intestinal Homing to Disrupt the Homeostasis of Intestinal Epithelial Cells in Crohn's Disease

Advanced Science, EarlyView.
In this study, we constructed a nanoparticle that was CD4 antibody‐mediated targeted, Fut7‐expressing plasmid‐loaded cationic liposome, namely CD4‐LDP‐Fut7. Upregulation of Fut7 expression in Tregs by using CD4‐LDP‐Fut7 can increase Treg homing to the intestine, thereby facilitating repair of the intestinal epithelial barrier and inhibiting ...
Qian Zhou, Xianfei Wang, Teng Ben, Chunping Zhu, Xinlong Lin, Yinmu Li, Xinyue Zhang, Yeling Chen, Yuchen Xuan, Huaiwen Chen, Ke Liu, Fang Wu, Yuexin Ren, Gao Tan   +13 more
wiley   +1 more source

A Combination of Flaxseed Oil and Astaxanthin Improves Hepatic Lipid Accumulation and Reduces Oxidative Stress in High Fat-Diet Fed Rats [PDF]

, 2017
Jiqu Xu, Shuang Rong, Hui Gao, Chang Chen, Wei Yang, Qianchun Deng, Qingde Huang, Lingyun Xiao, Fenghong Huang   +8 more
openalex   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

Black Soldier Fly Oil in Different Lipid Diets Could Regulate Tissue Lipid Metabolism and Fatty Acid Composition of Juvenile Mirror Carp

Aquaculture Nutrition
In the present study, our aim was to assess the effect of dietary black soldier fly oil (BSFO) with different lipid contents on the growth performance, body composition, lipid metabolism, and related gene expression in juvenile mirror carp (Cyprinus ...
Xinxin Xu, Beibei Ji, Ronghua Lu, Hong Ji   +3 more
doaj   +1 more source

Influence of Vegetarian and Nonvegetarian Diets on hs-CRP Levels, Lipid Profiles, and Cardiovascular Health in Adults

Journal of Pharmacy and Bioallied Sciences
Aim: The study aims to explore the impact of vegetarian and non-vegetarian diets on high-sensitivity C-reactive protein (hsCRP) levels and lipid profiles to understand how different dietary patterns contribute to heart health and inflammation. Objective:
Sunil Chakole, Namrata Anjankar, Ashish Anjankar, Harshal Narkhede, Sanket Mahajan   +4 more
doaj   +1 more source

A Cold Stress‐Activated Endocrine Sentinel Chemical Hormone Promotes Insect Survival via Mitochondrial Adaptations Through the Adipokinetic Hormone Receptor

Advanced Science, EarlyView.
Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou, Junxian Chen, Hongxia Zhang, Lu Guo, Kevin Mai, Elijah Abraham, Dilip V. Prajapati, Yue Chang, Jing Ning, Xinchen Wang, Defeng Li, Dan‐Dan Zhang, Jianghua Sun, Rebecca A. Butcher, Lilin Zhao   +14 more
wiley   +1 more source