Results 171 to 180 of about 317,795 (294)

Integration of nested cross-validation, automated hyperparameter optimization, high-performance computing to reduce and quantify the variance of test performance estimation of deep learning models. [PDF]

open access: yesComput Methods Programs Biomed
Calle P   +12 more
europepmc   +1 more source

High Performance Computing PP-Distance Algorithms to Generate X-ray Spectra from 3D Models. [PDF]

open access: yesInt J Mol Sci, 2022
González C   +7 more
europepmc   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

ScRNAbox: empowering single-cell RNA sequencing on high performance computing systems. [PDF]

open access: yesBMC Bioinformatics
Thomas RA   +4 more
europepmc   +1 more source

A high-performance MoS2 synaptic device with floating gate engineering\n for Neuromorphic Computing [PDF]

open access: green, 2019
Tathagata Paul   +4 more
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

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