Integration of nested cross-validation, automated hyperparameter optimization, high-performance computing to reduce and quantify the variance of test performance estimation of deep learning models. [PDF]
Calle P +12 more
europepmc +1 more source
High Performance Computing PP-Distance Algorithms to Generate X-ray Spectra from 3D Models. [PDF]
González C +7 more
europepmc +1 more source
Performance of pulmonary artery dimensions measured on high-resolution computed tomography scan for identifying pulmonary hypertension [PDF]
Pailin Ratanawatkul +3 more
openalex +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
ScRNAbox: empowering single-cell RNA sequencing on high performance computing systems. [PDF]
Thomas RA +4 more
europepmc +1 more source
Efficiency of Parallel Computing in High-Performance Applications in Germany
L.F. Hoffmann
openalex +2 more sources
A high-performance MoS2 synaptic device with floating gate engineering\n for Neuromorphic Computing [PDF]
Tathagata Paul +4 more
openalex +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source

