Results 81 to 90 of about 1,058,872 (427)

Determination of steroid estrogens in wastewater by high performance liquid chromatography-tandem mass spectrometry [PDF]

, 2007
This paper discusses the requirement for, and presents an analytical procedure for, the determination of four unconjugated steroid hormones and a conjugated steroid (estrone-3-sulfate) in wastewaters.
A. Boobis, Belfroid, Benijts, Benijts, Bones, Bowers, Cargouet, Croley, Desbrow, D’Ascenzo, E. Cartmell, Gentili, Gomes, Gomes, Hu, Huang, Ingrand, Isobe, J.N. Lester, Johnson, Johnson, Komori, Kramer, Kuch, Lagana, Lagana, Lai, Larsson, Lee, Lee, Liang, Lopez de Alda, Lopez de Alda, M.D. Scrimshaw, Petrovic, Purdom, Quintana, Reddy, Rodgers-Gray, Rodriguez-Mozaz, Rodriguez-Mozaz, Routledge, Salvador, Shishida, Shore, Snyder, Snyder, T.Y. Chiu, Tabak, Tang, Ternes, Ternes, Vieno, Y.K.K. Koh   +53 more
core   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Evolution through time of Pyrrolizidine Alkaloids detection and quantification [PDF]

arXiv, 2013
Pyrrolizidine Alkaloids (PAs) are a group of naturally occurring alkaloids that are produced by plants as a defense mechanism against insect herbivores. The analytical methodologies employed for their detection have come a long way since the first analytical experiment and in the last 30 years had an enormous development, both technological and ...
arxiv  

Monitorização do vale e pico sérico de vancomicina em recém-nascidos de termo: comparação entre as técnicas de cromatografia líquida de alta eficácia e imunoensaio por fluorescência polarizada [PDF]

, 2001
INTRODUCTION: Peak and trough serum concentrations of vancomycin were determined in term newborn infants with confirmed or suspected Staphylococcus sp sepsis by high performance liquid chromatography and flourescence polarization immunoassay.
Araújo, Maria C. K. de, Ceccon, Maria Esther J.R., Diniz, Edna Maria de Albuquerque, Feferbaum, Rubens, Krebs, Vera L. J., Machado, José Kleber Kobol, Okay, Thelma S., Santos, Silvia R. C. J., Vaz, Flávio Adolfo Costa   +8 more
core   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Analysis of polyamines in higher plants by high performance liquid chromatography.

Plant Physiology, 1982
A sensitive (0.01-1 nmol) method has been developed for the analysis of polyamines in higher plant extracts based on high performance liquid chromatography (HPLC) of their benzoyl derivatives (Redmond, Tseng 1979 J Chromatogr 170: 479-481).
H. Flores, A. Galston
semanticscholar   +1 more source

Measurement with High-Performance Liquid Chromatography (HPLC)

مجله دانشکده پزشکی اصفهان, 2015
Background: The global prevalence of diabetes mellitus is increasing rapidly. Measurement of glycated hemoglobin, predominantly HbA1c, is fundamental to the management of patients with diabetes. HbA1c is used to monitor long-term glycemic control, adjust
Azar Baradaran, Azadeh Karami
doaj  

Peak Alignment of Gas Chromatography-Mass Spectrometry Data with Deep Learning [PDF]

arXiv, 2019
We present ChromAlignNet, a deep learning model for alignment of peaks in Gas Chromatography-Mass Spectrometry (GC-MS) data. In GC-MS data, a compound's retention time (RT) may not stay fixed across multiple chromatograms. To use GC-MS data for biomarker discovery requires alignment of identical analyte's RT from different samples.
arxiv  

Comparison of green enhanced fluidity reversed phase liquid chromatography with HPLC [PDF]

, 2012
The growing interest in high throughput assays is the result of the increasing numbers and complexity of samples being produced by modern combinatorial synthetic procedures.
Admasu Engda, Engdawork, Brunelli, Claudio, Lynen, Frederic, Sandra, Patrick   +3 more
core