Results 241 to 250 of about 404,733 (304)

Alkyltransferase Ribozyme for Site‐Specific N4‐Cytidine Alkylation

Angewandte Chemie, EarlyView.
CSAR is the first ribozyme that catalyzes direct alkylation of an exocyclic amino group of an RNA nucleobase. The ribozyme was isolated as a self‐labeling catalyst from an in vitro selection library and engineered into a trans‐active ribozyme that catalyzes the transfer of a benzyl group from an O6‐modifed guanine to the N4 amino group of a specific ...
Evgeniia Dorinova, Manisha B. Walunj, Claudia Höbartner   +2 more
wiley   +1 more source

Different chromatographic techniques and recent advancements for biomedical and pharmaceutical applications. [PDF]

North Clin Istanb
Coskun O, Akbarzadeh S, Guncer B.
europepmc   +1 more source

Development and Validation of an Ion-Pair Reverse-Phase High-Performance Liquid Chromatography-Electrospray Ionization Mass Spectrometry Method for Determination of Purity of Nusinersen for Quality Control of Drug Substance or Drug Product. [PDF]

Int J Mol Sci
Samoilov M, Zubareva E, Degterev M.
europepmc   +1 more source

Modern Analytical Techniques in Epilepsy Research. [PDF]

Int J Mol Sci
Idzikowska K, Gątarek P, Kałużna-Czaplińska J.   +2 more
europepmc   +1 more source

Incorporation of Novel Synthetic Glycolipids in Liposomal Nanoparticles Affects Opsonization and In Vivo Clearance

Angewandte Chemie International Edition, EarlyView.
We prepared five glycosylated liposomal nanoparticles (G‐LNPs) to investigate the role of glycosylation and protein corona in modulating the in vivo behavior of G‐LNPs. We show that IgG and complement C3 adsorption enhanced liposomal nanoparticle clearance, with IgG promoting subsequent C3 binding.
Yingjie Yu, Xuehan Li, Yu Gao, Shijia Tao, Xiaofei Li, Lemei Zhao, Wenshuai Han, Hao Fan, Ying Qiu, Man Wang, Luying Zhou, Xiaoyan Fang, Wenhua Yang, Haiyang Zhang, Volker Mailänder, Daniel Crespy, Katharina Landfester, Shuai Jiang, Xiangzhao Mao   +18 more
wiley   +1 more source

A novel oxidation strategy using a palladium nanocatalyst for stabilizing bisacodyl in polyethylene glycol suppositories. [PDF]

Sci Rep
Kouhdareh J.
europepmc   +1 more source

Clarifying the active ingredients & pharmacological mechanisms of traditional Chinese medicines via modern pharmaceutical analysis techniques. [PDF]

J Pharm Anal
Zhou H, Yang F, Bai H, Lv Y, Wang C, Liu R, Yu H, Han S, Li Z.   +8 more
europepmc   +1 more source

Recent Advance in the Sample Pretreatments for Drug Analysis in Zebrafish. [PDF]

Pharmaceuticals (Basel)
Wang T, Wang C, Luo M, Wang X, Chen Y, Yang Z, Hu G, Liu W.   +7 more
europepmc   +1 more source

Optimization and Validation of an HPLC-PDA Method for the Determination of (6S)-5-Methyltetrahydrofolate in Diverse Dietary Supplement Formulations. [PDF]

Foods
Heo YJ, Cho GH, Song TW, Kim SJ, Im JH, Fu X, Lim JS, Kim MH, Suh HJ, Lee OH, Choi SI.   +10 more
europepmc   +1 more source

Comparative evaluation of oxidative stress biomarkers F2-isoprostanes and 8-OHdG in Parkinson's disease and Type 2 Diabetes Mellitus: a systematic review and meta-analysis of human studies. [PDF]

Ann Med
Msigwa SS, Mkwambe MC, Yu QY, Zhu SG, Zhu JH, Zhang X, Wang JY.   +6 more
europepmc   +1 more source