Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
The Study on the Key Elements in Strategic HRM: from Strategy to Organizational Performance
Ever since the end of last century, strategic HRM scholars have devoted a great and increasing deal of efforts to the exploration and examination of contributions of HRM practices/systems into organizational performance.
He Yunlan
doaj +1 more source
From validation to execution: Exploring the practical implementation of the conjoint framework of Quality Management and High-Performance Work Systems. [PDF]
Rehmani DK +3 more
europepmc +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Understanding the effects of high-performance work systems on productivity in small to medium enterprises (SMEs) can be critical to the sustainability of these firms in Zimbabwe.
Regis Misheal Muchowe +4 more
doaj +1 more source
High-Performance Work Systems and Coping Strategies in Regulating Burnout and Safety Workarounds in the Healthcare Sector. [PDF]
Waqar H, Mahmood A, Ali M.
europepmc +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
High Performance Work Systems, Justice, and Engagement: Does Bullying Throw a Spanner in the Works? [PDF]
Baillien E +3 more
europepmc +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
High-performance work systems (HPWS) and individual performance: The mediating role of commitment. [PDF]
Fragoso P, Chambel MJ, Castanheira F.
europepmc +1 more source

