Results 91 to 100 of about 15,654,964 (316)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Harnessing high altitude solar power [PDF]

, 2009
As an intermediate solution between Glaser's satellite solar power (SSP) and ground-based photovoltaic (PV) panels, this paper examines the collection of solar energy using a high-altitude aerostatic platform.
Markvart, T, Redi, S., Aglietti, GS, Markvart, T., Tatnall, A.R., Aglietti, G.S, Redi, S, Tatnall, AR   +7 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Impact of wind power on the unit commitment, operating reserves and market design

, 2011
Paper presented at the 2011 IEEE Power and Energy Society General Meeting, San Diego, CA, 24-29 July 2011This article highlights and demonstrates the new requirements variable and partly unpredictable wind power will bring to unit commitment and power ...
Milligan, M., Lange, B., Gibescu, M., Michael Milligan, Hannele Holttinen, Lange, Bernard, Kiviluoma, K., Juha Kiviluoma, Meibom, P., Meibom, Peter, O\u27Malley, Mark, Peter Meibom, Madeleine Gibescu, Kiviluoma, Juha; id_orcid, Tuohy, Aidan, Holttinen, H., Tuohy, A., Gibescu, Madeleine, Holttinen, Hannele, O'Malley, M., Milligan, Michael R., Bernhard Lange, Kiviluoma, Juha, Aidan Tuohy, O'Malley, Mark, Mark O'Malley   +25 more
core   +1 more source

Infrared spectrum target recognition and positioning technology based on image segmentation algorithm

Discover Artificial Intelligence
In the era of rapid development of digitalization and science and technology, infrared images are widely used in security, industry and other fields, but their target recognition and positioning face many difficulties. The existing image segmentation and
Runming He, Yu Wang, Zhenzhong Yan, Xiaoli Lu   +3 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

The role of power system flexibility in generation planning

, 2011
Paper presented at the IEEE 2011, Power and Energy Society General Meeting, San Diego, CA, 24-29 July 2011As the penetration of variable renewable generation increases in power systems worldwide, planning for the effects of variability will become more ...
Eamonn Lannoye, Lannoye, Eamonn, O\u27Malley, Mark, O'Malley, Mark, Mark O'Malley, Flynn, Damian, Damian Flynn   +6 more
core   +1 more source

Epitaxy of III-Nitrides on β-Ga₂O₃ and Its Vertical Structure LEDs

Micromachines, 2019
β-Ga2O3, characterized with high n-type conductivity, little lattice mismatch with III-Nitrides, high transparency (>80%) in blue, and UVA (400–320 nm) as well as UVB (320–280 nm) regions, has great potential as the substrate for ...
Weijiang Li, Xiang Zhang, Ruilin Meng, Jianchang Yan, Junxi Wang, Jinmin Li, Tongbo Wei   +6 more
doaj   +1 more source