Results 81 to 90 of about 2,660,702 (309)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Characteristic Analysis of Electromagnetic Force in a High-Power Wireless Power Transfer System

open access: yesEnergies, 2018
In order to explore the influence of the electromagnetic force (EMF) on the coupling mechanism in a high-power wireless power transfer (WPT) system, the characteristics of the EMF are investigated by theoretical calculation and simulation.
Xian Zhang   +4 more
doaj   +1 more source

Laser Cooled High-Power Fiber Amplifier

open access: yes, 2009
A theoretical model for laser cooled continuous-wave fiber amplifier is presented. The amplification process takes place in the Tm3+-doped core of the fluoride ZBLAN (ZrF4-BaF2-LaF3-AlF3-NaF) glass fiber. The cooling process takes place in the Yb3+:ZBLAN
Nemova, Galina
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Distribution Optimization Method for Power Environment-Friendly Mixed Insulation Gas

open access: yesZhongguo dianli
The state-of-art cost of environmental-friendly SF6/CF4 mixed insulating gas of GIS equipment in the power system is relatively high. In order to ensure its insulation and arc extinguishing performance, SF6 gas is overfilled on site, which is not in line
Jie DONG   +4 more
doaj   +1 more source

High-power Ka-band amplifier [PDF]

open access: yes
Development of a high-power tube suitable to power a Ka-band (34.5-GHz) antenna transmitter located at the Goldstone, California, tracking station is continuing.
Cormier, R.
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

High-power microwave optics for flexible power transmission systems [PDF]

open access: yes, 1980
A large concave microwave mirror near the transmitter can magnify the apparent size of the Earth as seen from a phased array, and vice versa, permitting a small phased array to be coupled to a small rectenna while preserving the transmission efficiency ...
Drexler, K. E., Sperber, B. R.
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

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