Results 81 to 90 of about 26,525,554 (339)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
High-power CW laser using hydrogen-fluorine reaction [PDF]
, 1975 Continuous-wave laser has been proposed based on reaction of hydrogen and fluorine. Hydrogen is produced by dissociation of hydrazine, which can be stored as liquid in light containers at room ...
Moynihan, P. I.
core +1 more source
Ultra-fast aqueous polymerisation of acrylamides by high power visible light direct photoactivation RAFT polymerisation [PDF]
, 2017 The effect of visible LED power (λmax = 402 nm, 451 nm) on kinetics and control of direct photoactivation RAFT polymerisations of acrylamide and dimethylacrylamide are investigated.
Cameron, Neil R. +4 more
core +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Stabilized High Power Laser for Advanced Gravitational Wave Detectors [PDF]
, 2006 Second generation gravitational wave detectors require high power lasers with several 100W of output power and with very low temporal and spatial fluctuations.
Danzmann, K. +10 more
core +3 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
IEEE Photonics Journal, 2018 A high-power, high-efficiency, and high-speed white light-emitting-diode (LED) wireless transmitter is presented in this paper. This transmitter system consists of a gallium nitride field effect transistor (GaN FET) driver with push–pull structure,
Yicheng Wu +4 more
doaj +1 more source
Full Band Compact Power Arm Subsystem With High Directive Sample
IEEE Access, 2020 An output arm is the first subsystem in the microwave components chain connected immediately after the power amplifier. These arms are responsible for transferring the signal from the output port of the power amplifier to the standard line of the system.
Mahmoud Elsaadany +4 more
doaj +1 more source
Towards Quantitative Simulations of High Power Proton Cyclotrons
, 2010 PSI operates a cyclotron based high intensity proton accelerator routinely at an average beam power of 1.3MW. With this power the facility is at the worldwide forefront of high intensity proton accelerators.
Adelmann, A. +6 more
core +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source