Results 61 to 70 of about 19,074,800 (301)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Currently baby food is sterilized using retort processing that gives an extended shelf life. However, this type of heat processing leads to reduction of organoleptic and nutrition value.
Farid, Mohammed +5 more
core +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Inactivation of Escherichia coli in milk by high pressure processing at low and subzero temperatures
Inactivation of Escherichia coli strain ATCC 25922 in frozen and unfrozen milk by high pressure processing at low or subzero temperatures was investigated.
Bulut, Sami
core +1 more source
High pressure falling sinker liquid viscosity determination without supplementary density data : a new approach [PDF]
Accurate measurement and determination of liquid viscosity data under high pressure conditions requires knowledge of liquid density data. In this study, a high pressure falling sinker-type viscometer was used to determine the viscosity of n-dodecane at ...
Schaschke, C.J., Zeng, Minyu
core +2 more sources
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
This present volume contains the text of all contributions (oral and posters), except for the four invited papers, which were presented at the 3rd International Symposium on High Pressure Chemical Engineering on October 7-9, 1996.
Trepp, Ch. +2 more
core
Compositional, mechanical and transport properties of carbonate fault rocks and the seismic cycle in limestone terrains: A case study of surface exposures on the Longmenshan Fault, Sichuan, China [PDF]
Destructive earthquakes are common in tectonically active regions dominated by carbonate cover rocks. The catastrophic Wenchuan earthquake that struck Sichuan, China, also affected a section of carbonate cover terrain.
Chen, Jianye +2 more
core
High hydrostatic pressure is a non-thermal food processing technology, which also has several successful applications in different areas besides food processing. In this study, Capsicum annuum L.
Işlek C., Altuner E.M., Alpas H. +1 more
core +1 more source

