Results 151 to 160 of about 8,262,455 (292)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Advances in agricultural high-quality development
Open Access Journal of Agricultural ResearchAgricultural development has gone through a long time. According to the efficiency plant use nature resources, the whole process of agricultural development can be divided into three stages: Low level development stage or primitive agriculture, Level improvement stage and new stage of agriculture high-quality development.
openaire +1 more source
Can Foreign Producers Benefit from Geographical Indications under the New European Regulation? [PDF]
This article discusses some economic issues linked to the 2006 European regulation regarding geographical indications. Economic implications of this regulation for foreign producers are investigated. The article examines whether or not the development of
Marette, Stephan
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Road development, economic growth, and poverty reduction in China [PDF]
"Since 1978, China has adopted a series of economic reforms leading to rapid economic growth and poverty reduction. National Gross Domestic Product (GDP) grew at about 9 percent per annum from 1978 to 2002, while per capita income increased by 8 percent ...
Chan-Kang, Connie, Fan, Shenggen
core
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Multiple causal pathways of high-quality development for semiconductor enterprises in China. [PDF]
PLoS OneLi S, Yang X.
europepmc +1 more source
High-quality Curriculum Resources Support the High-quality Development of Rural Education
Region - Educational Research and ReviewsEducational equity and quality are important goals of educational modernization. For a long time, due to factors such as geographical location and economic conditions, the overall development level of rural education in China has lagged behind, facing many difficulties such as insufficient teaching staff, shortage of teaching resources, and backward ...
openaire +1 more source