Results 101 to 110 of about 1,467,276 (295)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Aspects of Radar Imaging Using Frequency-Stepped Chirp Signals

EURASIP Journal on Advances in Signal Processing, 2006
The high-resolution, frequency-stepped chirp signal can be applied to radar systems employing narrow-bandwidth chirp pulses, in order to enhance the range resolution, and to implement SAR/ISAR imaging capabilities.
Jin Ya-Qiu, Zhang Qun
doaj   +1 more source

Inhomogeneous distribution of mercury on the surfaces of rapidly rotating HgMn stars

, 2005
Starspots are usually associated with the action of magnetic fields at the stellar surfaces. However, recently an inhomogeneous chemical distribution of mercury was found for the mercury-manganese (HgMn) star alpha And -- a well-established member of a ...
Kochukhov, O., Kudryavtsev, D., Piskunov, N., Sachkov, M.   +3 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Multi-Dimensional Parameter-Estimation Method for a Spatial Target Based on the Micro-Range Decomposition of a High-Resolution Range Profile

Remote Sensing
The high-precision estimation of multi-dimensional parameters for spatial targets based on high-resolution range profiles is crucial for target recognition.
Xing Wang, Degui Yang, Zhichen Zhao
doaj   +1 more source

The edge of the M87 halo and the kinematics of the diffuse light in the Virgo cluster core

, 2009
We present high resolution FLAMES/VLT spectroscopy of intracluster planetary nebula (ICPN) candidates, targeting three new fields in the Virgo cluster core with surface brightness down to mu_B = 28.5.
Aguerri, J. Alfonso L., Arnaboldi, Magda, Ciardullo, Robin, Das, Payel, Doherty, Michelle, Feldmeier, John J., Freeman, Kenneth C., Gerhard, Ortwin, Jacoby, George H., Murante, Giuseppe   +9 more
core   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Single-cycle atomic force microscope force reconstruction: resolving time-dependent interactions

New Journal of Physics, 2013
Here, we enhance the capabilities of the atomic force microscope (AFM) to show that force profiles can be reconstructed without restriction by monitoring the wave profile of the cantilever during a single oscillation cycle. Two approaches are provided to
Sergio Santos, Karim Gadelrab, Josep Font, Matteo Chiesa   +3 more
doaj   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Enhancing Scattering Center Visibility for ISAR-Based Ballistic Missile Identification [PDF]

Journal of Electromagnetic Engineering and Science
The immense threat posed by ballistic missiles has prompted many nations to develop ballistic missile defense systems. To operate these defense systems effectively, it is essential to quickly identify the missile type in flight and prioritize responses ...
Jaehyuk Kang, Sung-Geon Kim, Seulgi Koh, Ic-Pyo Hong, Hyun-Sung Tae, Jong-Gwan Yook   +5 more
doaj   +1 more source