Results 41 to 50 of about 16,837,471 (302)

High‐Resolution UV Spectroscopy of Molecular Complexes [PDF]

Berichte der Bunsengesellschaft für physikalische Chemie, 1992
AbstractInformation on the structure, the rigidity and the intermolecular potential of molecular complexes is essential to our understanding of the physical and chemical properties of molecular complexes. In this work we would like to demonstrate that rotationally resolved UV spectroscopy provides precise new information on these topics. In particular,
Neusser, H. J., Sußmann, R., Smith, A. M., Riedle, E., Weber, Th.   +4 more
openaire   +3 more sources

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Optical fiber sensing based on reflection laser spectroscopy [PDF]

, 2010
An overview on high-resolution and fast interrogation of optical-fiber sensors relying on laser reflection spectroscopy is given. Fiber Bragg-gratings (FBGs) and FBG resonators built in fibers of different types are used for strain, temperature and ...
De Natale, Paolo, Ralph P. Tatam, Chow, Jong H., Jong H. Chow, Mario Salza, Ballard, Nicholas, Gangopadhyay, Tarun, Paz-Soldan, Daniel, Tatam, Ralph, Ferarro, Pietro, Lam, Timothy T. -Y., Lam, Timothy T-Y, Gianluca Gagliardi, Barnes, Jack A., Daniel Paz-Soldan, Gangopadhyay, Tarun Kumar, Tatam, Ralph P., Chow, Jong, Pietro Ferraro, Tarun K. Gangopadhyay, Jack A. Barnes, Loock, Hans-Peter, Edmond Chehura, Paolo De Natale, Gangopadhyay, Tarun K., Salza, Mario, Ferraro, Pietro, Hans-Peter Loock, Nicholas Ballard, Barnes, Jack, Chehura, Edmon, Gagliardi, Gianluca, Timothy T.-Y. Lam, Lam, Timothy, Chehura, Edmond   +34 more
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

High-precision Near-infrared Abundances of Solar Analogs in the YJ Bands

The Astrophysical Journal Supplement Series
We present a near-infrared abundance analysis of 46 solar analogs with known ages, observed with the WINERED WIDE-mode spectrograph at a resolution of λ /Δ λ  = 28,000.
Noriyuki Matsunaga, Takuji Tsujimoto, Daisuke Taniguchi, Hiroaki Sameshima, Shogo Otsubo, Tomomi Takeuchi, Yuki Sarugaku, Ilaria Petralia, Scarlet Elgueta, Matilde Coello-Guzmán, Kei Fukue, Yuji Ikeda, Hideyo Kawakita, Valentina D’Orazi, Giuseppe Bono   +14 more
doaj   +1 more source

High-resolution neutron spectroscopy on protein solution samples

EPJ Web of Conferences, 2015
Proteins in solution move subject to a complex superposition of global translational and rotational diffusion as well as internal relaxations covering a wide range of time scales. With the advent of new high-flux neutron spectrometers in combination with
Grimaldo Marco, Roosen-Runge Felix, Jalarvo Niina, Zamponi Michaela, Zanini Fabio, Hennig Marcus, Zhang Fajun, Schreiber Frank, Seydel Tilo   +8 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Fast acquisition of high resolution liquid NMR spectroscopy

Magnetic Resonance Letters
Nuclear magnetic resonance (NMR) spectroscopy is a powerful tool for analyzing molecular structure and composition. However, traditional NMR experiments suffer from long acquisition times, especially in multidimensional NMR spectroscopy. This problem, to
Wen Zhu, Mengjie Qiu, Yao Luo, Xiaoqi Shi, Zhong Chen, Yanqin Lin   +5 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source