Results 111 to 120 of about 12,865,199 (315)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Säker storskalig vätgasbunkring - Test och validering [PDF]

open access: yes
Safe large scale hydrogen bunkering - Test and validation The project investigates the use of green hydrogen as a sustainable fuel for shipping. It focuses on developing and validating a new cylinder design with built-in cooling to handle temperature ...
Engberg, David   +6 more
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Kvantifiering av Resiliens : För att identifiera och säkra resiliens, med exempel för tillämpning med AI [PDF]

open access: yes
Denna rapport presenterar en skalbar metod för att kvantifiera resiliens i produktionssystem genom att uttryckligen kombinera mjuka (organisatoriska) och hårda (tekniska) aspekter per faktor n:Rn = Mn × Hn, med totalresiliens T = ∏Rn.
Carlsson, Raul
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Regulatorisk försöksverksamhet : Förstudie om regulatoriska sandlådor som verktyg för klimatomställning i Helsingborgs stad [PDF]

open access: yes
Syftet med förstudien är att skapa ett kunskapsunderlag för hur försöksverksamhet – med särskilt fokus på regulatoriska lösningar – kan användas som verktyg för att främja innovation och klimatomställning i stadsutvecklingen.
Thidevall, Niklas   +3 more
core  

Safety Climate in High-Rise Construction

open access: yesBuildings
This study examines safety climate perceptions in construction using two models: the Safety Climate Model (SCM) and the Nordic Safety Climate Questionnaire (NOSACQ-50).
Igal M. Shohet, Roi Naveh, Fadi Shahin
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Background report of ex-ante LCAs for CBE JU application IRIS [PDF]

open access: yes
To assess the environmental sustainability aspects of the IRIS technologies, ex-ante LCAs were carried out, considering a broad range of environmental impact categories like climate, resource efficiency and pollution (emissions to air, soil and water ...
Hammar, Torun   +2 more
core  

Home - About - Disclaimer - Privacy