Results 91 to 100 of about 18,160,165 (346)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Performance Characteristics of the Steels for High-Rise Buildings

open access: yes, 2011
With the development of high-rise buildings, the requirement to the performance of steels for high-rise buildings keeps on increasing. Besides high strength and high toughness possessed by general structural steels, the steels for high-rise buildings ...
Qing Bo Yu
core   +1 more source

Understanding Compartmentation Failure for High-Rise Timber Buildings

open access: yesFire
The traditional concept of compartmentation guaranteed by fire resistance is mainly concerned with the problem of destructive internal spread potential. External convective spread potential pertains to the loss of compartmentation associated with windows
Agustín H. Majdalani   +3 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Eco-sensitive energy dimention of high-rise buildings in tropical climate

open access: yes, 2007
One of the greatest challenges in South Asia is to adapt building types evolved in temperate climates to the rigors of tropical climate. High-rise buildings specially adapted to the regional climate and open-air lifestyle would punctuate the pattern ...
Senevirathne, SMMK
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Measuring Airtightness of High-Rise Buildings (Lessons Learned)

open access: yesBuildings
Measuring the airtightness of high-rise buildings presents significant challenges due to the effects of wind and thermal lift (stack effect). Small indoor/outdoor temperature differences, combined with the building’s height, can create substantial ...
Stefanie Rolfsmeier   +3 more
doaj   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Verification of the energy flow analysis method as identification tool for damping in High-Rise Buildings

open access: yes, 2019
Damping is an important parameter in the calculation of vibrations in high-rise buildings. This research presents a verification study of the Energy Flow Analysis as identification tool for damping in high rise buildings.
Suiker, A.   +3 more
core  

The fire in high rise buildings

open access: yesInformes de la Construccion, 1987
From the point of view of fire protection the high rise buildings have a special consideration, according to their design activities carried on, and fire protection system installed in them. In high rise buildings, difficulty of access by Extinction Services should be taken into account, as well as the impossibility of proceeding to make total ...
Núñez Astray, F.   +3 more
openaire   +1 more source

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