Results 81 to 90 of about 18,160,165 (346)

Space Efficiency in European High-Rise Timber Buildings

Applied Sciences
As towering wooden edifices (≥8 stories) become a rapidly expanding and promising field, they provide substantial environmental and economic advantages throughout their entire lifespans, leading to their increasing popularity, especially in the European ...
Hüseyin Emre Ilgın, Özlem Nur Aslantamer   +1 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

The adaptability of evolving green high-rise construction: embodied energy dynamics in Australian high-rise buildings

International Journal of Sustainable Energy, 2022
This paper intends to establish what is the most influential embodied energy factor, materials, or construction process for high-rise buildings. This study evaluates the performance of 20 green buildings across Australia.
Koorosh Gharehbaghi, Ken Farnes, Lada Kucharski, Sofia Fragomeni   +3 more
doaj   +1 more source

Effect of Rising Seismic Risk on the Design of High Rise Buildings in Karachi [PDF]

, 2012
Earthquake is an unexpected event which cannot be predicted earlier. The only way to survive through this disaster is by taking careful considerations while planning and designing buildings in urban areas.
Zehra, Yasmeen, Zahra, Tatheer
core  

The Influence of High-Rise Buildings on Pedestrian-Level Wind in Surrounding Street Canyons in an Urban Renewal Project

, 2020
The pedestrian wind environment in a street canyon is affected by a multitude of factors, including the height and geometric shape of the surrounding buildings, the street width, the wind direction, and speed.
Chun-Ta Tzeng, Tzu-Ling Huang, Chi-Ming Lai, Chien-Yuan Kuo   +3 more
core   +1 more source

AERODYNAMICS EVALUATION OF HIGH-RISE BUILDINGS

Journal of Industrial Design and Engineering Graphics
Due to the increasing population density in metropolitan areas, architects have focused on high rise building designs that combine architectural considerations with functional requirements.
Iacob-Liviu SCURTU, Alexandra-Daniela SCURTU   +1 more
doaj   +2 more sources

ECOSUSTAINABLE HIGH-RISE : The Environmentally Conscious Architecture of Skyscraper

Dimensi: Journal of Architecture and Built Environment, 2000
The term " green architecture " is related to evolving architecture which is sensitive to the environment and emerges from the environmental awareness due to the effects of destruction of air, water, energy and earth.
Jimmy Priatman
doaj  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Sustainable Development of Recent High-Rise Timber Buildings

High-rise timber building construction is becoming increasingly common across the world as construction and woodworking technology advances. The world is moving toward more sustainable development, and products like cross-laminated timber offer ...
Bahrami, Alireza, Rashid, S. M. Priok, Rashid, S. M. Priok,, Bahrami, Alireza,   +3 more
core   +1 more source