Results 61 to 70 of about 680,654 (265)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

The support systems of unique high-rise buildings

MATEC Web of Conferences, 2017
Tall buildings and skyscrapers perceive significant vertical loads and, moreover, have to resist large lateral effects which form strong gusts of wind and seismic events. In the world for the high-rise buildings with the nuclei of the stiffness are using
Shumeyko Victor
doaj   +1 more source

Continuous Monitoring of High‐Rise Buildings Using Seismic Interferometry [PDF]

, 2018
The linear seismic response of a building is commonly extracted from ambient vibration measurements. Seismic deconvolution interferometry performed on ambient vibrations can be used to estimate the dynamic characteristics of a building, such as its shear-
Buyukozturk, Oral, Büyüköztürk, Oral, Mordret, Aurelien, Prieto Gomez, German, Sun, Hao, Toksoz, M. Nafi   +5 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

AERODYNAMICS EVALUATION OF HIGH-RISE BUILDINGS

Journal of Industrial Design and Engineering Graphics
Due to the increasing population density in metropolitan areas, architects have focused on high rise building designs that combine architectural considerations with functional requirements.
Iacob-Liviu SCURTU, Alexandra-Daniela SCURTU   +1 more
doaj   +2 more sources

THE EFFECT OF BEHAVIOUR FACTOR ON THE SEISMIC PERFORMANCE OF LOW-RISE AND HIGH-RISE RC BUILDINGS [PDF]

, 2017
This study investigates the performance of RC buildings designed according to Eurocode 8. Two families of RC buildings (i.e., 3 storey and 18 storey) are investigated using nonlinear static or push over analysis (POA).
A. Majid, Taksiah, Faisal, Ade, Mohd Zahid, Mohd Zulham Affandi   +2 more
core   +1 more source

Effects of differential axial shortening on outrigger systems in high rise buildings with concrete filled steel tube columns [PDF]

, 2015
Concrete Filled Steel Tube (CFST) columns are popular in high rise buildings due to their superior strength, seismic and fire resistance capacities and construction simplicity.
Chan, Tommy H. T., Moragaspitiya, Praveen H. N., Samarakkody, Dilrukshie I., Thambiratnam, David P.   +3 more
core   +2 more sources

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Space Efficiency in European High-Rise Timber Buildings

Applied Sciences
As towering wooden edifices (≥8 stories) become a rapidly expanding and promising field, they provide substantial environmental and economic advantages throughout their entire lifespans, leading to their increasing popularity, especially in the European ...
Hüseyin Emre Ilgın, Özlem Nur Aslantamer   +1 more
doaj   +1 more source

The adaptability of evolving green high-rise construction: embodied energy dynamics in Australian high-rise buildings

International Journal of Sustainable Energy, 2022
This paper intends to establish what is the most influential embodied energy factor, materials, or construction process for high-rise buildings. This study evaluates the performance of 20 green buildings across Australia.
Koorosh Gharehbaghi, Ken Farnes, Lada Kucharski, Sofia Fragomeni   +3 more
doaj   +1 more source