Results 51 to 60 of about 680,654 (265)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Utilization of Intelligent Facade Technologies in High-rise Office Buildings: A Comparative Study

Iconarp International Journal of Architecture and Planning
In the late 19th century, spurred by the Industrial Revolution and the concomitant rise in population and technological advancements, high-rise buildings began to emerge in urban centers.
Fazilet Tuğrul Okbaz, Simay Aydinç, Ferhat Pakdamar   +2 more
doaj   +1 more source

Progressive Collapse of High-Rise Buildings from Fire

MATEC Web of Conferences, 2016
Considers ensuring the stability of structures of high-rise buildings against progressive collapse due to fire, proposed measures to ensure the stability of high-rise buildings due to progressive collapse.
Pershakov Valerii, Bieliatynskyi Andrii, Popovych Ivanna, Lysnytska Katerina, Krasheninnikov Vladimir   +4 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Floor-level premiums in high-rise and low-rise buildings [PDF]

, 2006
This paper examines a unique feature of multi-storey buildings – floor-level premiums. Floor-level premiums refer to the price paid for the vertical location of a flat, measured by its floor level.
Chau, KW, Cheung, KC, Wong, SK, Yau, Y
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Impact of solar shading geometry on building energy use in hot humid climates with special reference to Malaysia [PDF]

, 2005
External solar shading devices can substantially reduce the cooling load of buildings and large energy savings can be achieved. Hence, intercepting the radiant heat wave before penetrating to the internal environment through envelope openings is the main
Ahmad, M. Hamdan, Madros, Nor Haliza, R. Ossen, Dilshan   +2 more
core  

Effect of soft story on structural response of high rise buildings. [PDF]

, 2011
Severe structural damage suffered by several modern buildings during recent earthquakes illustrates the importance of avoiding sudden changes in lateral stiffness and strength.
Abang Ali, Abang Abdullah, Chieng, C. Y., Hejazi, Farzad, Jaafar, Mohd Saleh, Kojouri, Samira Jilani, Noorzaei, Jamaloddin   +5 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Horizontally connected high-rise buildings under earthquake loadings

Ain Shams Engineering Journal, 2019
Responses to lateral loads induced by wind and earthquakes are among the governing factors in the structural design of these structures. In the current trend, adjacent tall buildings are being horizontally connected for different purposes.
Sayed Mahmoud
doaj   +1 more source