Results 191 to 200 of about 1,227,499 (265)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Conformable Fractional Deep Neural Networks (CFDNN) for high-speed cyber-attack detection. [PDF]

Sci Rep
Ajarmah B, Iwidat H.
europepmc   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

High-speed multiplexed DNA-PAINT imaging of nuclear organization using an expanded sequence repertoire. [PDF]

Nat Commun
Banerjee A, Anand M, Srivastava M, Vidwath VS, Ganji M.   +4 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Difference Between Low-Speed and High-Speed Rotational Atherectomy Using Two Types of Guidewires. [PDF]

Catheter Cardiovasc Interv
Kawamura A, Okayama K, Nohara H, Nakano T, Sakata Y.   +4 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Motion Blur-Free High-Speed Hybrid Image Sensing. [PDF]

Sensors (Basel)
Park PKJ, Kim J, Ko J.
europepmc   +1 more source

Single-Molecule Visualization of DNase I-Mediated DNA Cleavage by High-Speed Atomic Force Microscopy. [PDF]

ACS Chem Biol
Elessawy N, Sinan S, Zhang H, Yang Z, Lu Y, Finkelstein IJ, Lin YC.   +6 more
europepmc   +1 more source

High-Speed Detection of X-ray Pulses Using a Digital Counter Coupled with Perovskite Composite Scintillators. [PDF]

ACS Appl Mater Interfaces
Khaliq S, Faleiros MC, Zhang L, Hasanov BE, de Oliveira Filho JI, Bayindir M, Bakr OM, Salama KN, Mohammed OF.   +8 more
europepmc   +1 more source