Results 201 to 210 of about 36,236,534 (364)

Deep learning-based high-speed railway communication systems. [PDF]

Sci Rep
Ha DV, Chien TV, Ngo HQ.
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Synaptic high-frequency jumping synchronises vision to high-speed behaviour. [PDF]

Nat Commun
Mansour N, Takalo J, Kemppainen J, Bridges AD, MaBouDi H, Asgar Bohra A, Anielska K, Vasas V, Robert T, Yi Bu B, Shukla S, Zhou Y, Kittelmann M, Ouwendijk J, Mantell J, Lawson M, de Polavieja G, Duke E, Lazar AA, Verkade P, Chittka L, Juusola M.   +21 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Analysis of Shear Localization in High-Speed Blanking of Press-Hardened 22MnB5 Steel

High-speed blanking induces a shear localization in high-strength steels, improving the quality of the blanked edge in terms of geometrical shape, separation surface roughness, and shear-influenced zone close to the cut edge.
Dardaei Joghan, H., Tekkaya, A. E., Korkolis, Y. P., Schrage, O., Hahn, M.   +4 more
core   +1 more source

Development of a high-speed planetary gearbox for an electric vehicle. [PDF]

Sci Rep
Zagirnyak M, Drahobetskyi V, Salenko Y, Kulynych V, Moloshtan D, Szczęsny A, Korzeniewska E.   +6 more
europepmc   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Tyzx DeepSea High Speed Stereo Vision System

, 2004
This paper describes the DeepSea Stereo Vision System which makes the use of high speed 3D images practical in many application domains. This system is based on the DeepSea processor, an ASIC, which computes absolute depth based on simultaneously ...
High Speed, Stereo Vision System, Tyzx Deepsea, John Iselin Woodfill   +3 more
core  

High-Speed Volumetric Dual-Mode Ultrasound and Photoacoustic Tomography With a Single-Element Detector. [PDF]

IEEE Trans Med Imaging
Basumatary J, Aborahama Y, Zhang Y, Zhang Y, Zeng Y, Liu CZ, Zhou Q, Wang LV.   +7 more
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source