Results 141 to 150 of about 56,741 (293)

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

open access: yesAdvanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang   +7 more
wiley   +1 more source

Chemical constituents from Wedelia prostrata and their cytotoxicity activity [PDF]

open access: yes, 2016
卤地菊(Wedeliaprostrata(Hook.etArn.)Hemsl.)为菊科蟛蜞菊属植物。对蟛蜞菊属植物研究调查表明,其主要含有二萜,倍半萜,黄酮和有机酸等化学成分。二萜尤其是对映-贝壳杉二萜类是蟛蜞菊属植物的主要活性成分,具有抗菌、抗病毒、抗氧化、抗癌、抗血管生成等生物活性。 本文首先用石油醚、乙酸乙酯、正丁醇三种不同极性的溶剂依次对卤地菊的乙醇提取物进行萃取,初步得到三个萃取部位,对卤地菊石油醚部位进行系统的化学成分研究,采用硅胶柱层析、聚酰胺柱层析、葡聚糖凝胶柱层析 ...
林剑虹
core  

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

open access: yesAdvanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li   +23 more
wiley   +1 more source

A survey and analysis of commercially available hydrogen sensors [PDF]

open access: yes
The performance requirements for hydrogen detection in aerospace applications often exceed those of more traditional applications. In order to ascertain the applicability of existing hydrogen sensors to aerospace applications, a survey was conducted of ...
Hunter, Gary W.
core   +1 more source

Index to NASA Tech Briefs, January - June 1967 [PDF]

open access: yes, 1967
Technological innovations for January-June 1967, abstracts and subject ...

core   +1 more source

A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes

open access: yesAdvanced Science, EarlyView.
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen   +13 more
wiley   +1 more source

Spacecraft nitrogen generation [PDF]

open access: yes
Two spacecraft nitrogen (N2) generation systems based on the catalytic dissociation of hydrazine (N2H4) were evaluated. In the first system, liquid N2H4 is catalytically dissociated to yield an N2 and hydrogen (H2) gas mixture.
Carlson, J. N.   +3 more
core   +1 more source

Promotion of DFU Wound Healing via BRG1–COL16A1 Axis in Fibroblasts

open access: yesAdvanced Science, EarlyView.
In normal wound healing, transcription factor BRG1 is upregulated and binds the COL16A1 promoter to enhance its expression, promoting fibroblast proliferation, migration, contraction, extracellular matrix deposition, and granulation tissue formation, thus accelerating wound closure.
Penghui Wang   +10 more
wiley   +1 more source

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