Results 31 to 40 of about 10,767,370 (303)

Power of the policy: how the announcement of high-stakes clinical examination altered OSCE implementation at institutional level

open access: yesBMC Medical Education, 2013
Background The Objective Structured Clinical Examination (OSCE) has been widely applied as a high-stakes examination for assessing physicians’ clinical competency.
Lin Chi-Wei   +4 more
doaj   +1 more source

High Stakes, Serious Noticing [PDF]

open access: yesAMA Journal of Ethics, 2020
Behind the immediate pathophysiology of a medical condition often lies the emotional turmoil of an uncertain patient. As a result, many patients suffer from distressing thoughts and emotions, and their caregivers play an important role in comforting them.
openaire   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Forty Years of Public Opinion on Standardized Testing

open access: yesNonpartisan Education Review, 2006
no ...
Richard P. Phelps
doaj  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

The readability of a high stakes Physics examination paper

open access: yesActa Academica, 2012
This article reports on the readability of a Physics examination paper written by grade-12 students. A sample of 500 scripts was analysed for readability problems associated with linguistic features synonymous with scientific writing. The study revealed
Umesh Ramnarain
doaj   +3 more sources

Validation of the Principal’s High Stakes Testing Survey

open access: yesGeorgia Educational Researcher, 2009
The purpose of this study was to examine the soundness of the psychometric characteristics of the Principal’s High Stakes Testing Survey. The 48-item instrument is comprised of six hypothesized subscales (i.e., curriculum, teaching, work satisfaction ...
Lantry Brockmeier, James Pate, Don Leech
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

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