Results 51 to 60 of about 286,996 (314)

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak, Marije M. C. Voermans, Hans Heijst, Charlotte E. Teunissen, Marc Engelen   +4 more
wiley   +1 more source

Analysis of concrete-filled steel tubes with high-strength materials under sustained loading

, 2018
Over the past few decades, concrete-filled steel tubular (CFST) columns have gained increasing popularity in building construction, due to their significant structural and economic benefits over conventional steel and reinforced concrete columns.
Li, Dongxu, Hamed, Ehab, Uy, Brian, Tao, Zhong (R12091), Kang, Won-Hee (R16823)   +4 more
core   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Experimental Study and Prediction Model of Low Temperature Mechanical Properties of High-Strength Steel

Shanghai Jiaotong Daxue xuebao
The application of high-strength steel in extremely cold polar regions can reduce steel consumption and save the cost of fabrication, transportation, and installation of steel structures in the harsh low-temperature environment.
CAI Ao, CHEN Mantai, ZUO Wenkang, DUAN Liping, ZHAO Jincheng
doaj   +1 more source

Behaviour and design of composite beams subjected to negative bending and compression [PDF]

, 2012
This paper investigates the behaviour of steel–concrete composite beams subjected to the combined effectsof negative bending and axial compression. For this study, six full-scale tests were conducted on compositebeams subjected to negative moment while ...
Uy, Brian (R9735), Vasdravellis, George; id_orcid, Kirkland, Brenadan, Uy, Brian, Vasdravellis, George (R16696), Tan, Ee Loon (R14425), Tan, Ee Loon, Kirkland, Brendan (S24876)   +7 more
core   +1 more source

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

Comparative study on dynamic mechanical properties of additive manufacturing high strength steel and wrought high strength steel under high strain rate

Journal of Materials Research and Technology
Additive manufacturing high-strength steel has a unique manufacturing process and has broad application prospects in military equipment, aerospace, and other fields, but it is often threatened by dynamic loads such as explosion and high-speed impact ...
Zheng-qing Zhou, Pei-ze Zhang, Yu-long Zhang, Bin Hu, Xing-bo Xie, Gui-li Yang, Ming-shou Zhong, Jia Liu, Zhi-ming Bai   +8 more
doaj   +1 more source

Mechanical properties of high-strength HTRB600 steel bars under high temperature

工程科学学报, 2017
Tensile testing of HTRB600 steel bars under high temperature was conducted to determine the mechanical properties of the steel under high temperature. The elastic modulus, proportional limit, yield strength, ultimate strength, and stress-strain curves of
GONG Wei, HU Ke-xu, WANG Yi-di
doaj   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Influence of microstructure on fatigue property of ultra high-strength steels

Fracture and Structural Integrity, 2019
Ultra-high-strength steels (with tensile strength higher than 980 MPa) are widely used in automobile manufacturing owing to their lightweight that contributes to fuel efficiency.
Kanji OKUDA, Kazuhiro OGAWA, Yuji ICHIKAWA, Tsuyoshi SHIOZAKI, Naoki YAMAGUCHI   +4 more
doaj   +3 more sources