Results 131 to 140 of about 11,387,151 (316)

Is High Throughput Glycomics Possible?

Mass Spectrometry, 2013
The role of glycosylation and their biological functions whether as free oligosaccharides or glycoconjugates has been made possible by the recent advancements in the analyses of these compounds. The heterogeneity and the large structural diversity have made oligosaccharide analysis significantly more difficult than other biopolymers.
openaire   +3 more sources

What Do Large Language Models Know About Materials?

Advanced Engineering Materials, EarlyView.
If large language models (LLMs) are to be used inside the material discovery and engineering process, they must be benchmarked for the accurateness of intrinsic material knowledge. The current work introduces 1) a reasoning process through the processing–structure–property–performance chain and 2) a tool for benchmarking knowledge of LLMs concerning ...
Adrian Ehrenhofer, Thomas Wallmersperger, Gianaurelio Cuniberti   +2 more
wiley   +1 more source

Malignant pleural effusion facilitates the establishment and maintenance of tumor organoid biobank with multiple patient-derived lung tumor cell sources

Experimental Hematology & Oncology
The Patient-Derived Organoids (PDOs) has demonstrated significant potential in personalized medicine. However, the initial establishment of lung cancer organoids (LCOs), and timely therapeutic recommendations face several challenges.
Lingwei Wang, Yanli Yu, Yanhua Fang, Yanjiao Li, Weiting Yu, Zhe Wang, Jinyan Lv, Ruoyu Wang, Shanshan Liang   +8 more
doaj   +1 more source

Productivity‐Driven Optimization of Laser Powder Bed Fusion Parameters for IN718 Superalloy: Process Control, Microstructure, and Mechanical Properties

Advanced Engineering Materials, EarlyView.
This study demonstrates how optimizing laser power, scanning speed, and hatching distance in laser powder bed fusion can boost the productivity of Inconel 718 manufacturing by up to 29% while maintaining mechanical integrity. The work delivers a validated process window and cost–time analysis, offering industry‐ready guidelines for efficient additive ...
Amir Behjat, Guido Barale, John Stavridis, Ehsan Norouzi, Jin‐Yoo Suh, Dong‐Ik Kim, Luca Iuliano, Abdollah Saboori   +7 more
wiley   +1 more source

Field Report from Collaborative Research Center 1625: Heterogeneous Research Data Management Using Ontology Representations

Advanced Engineering Materials, EarlyView.
A unified research data management framework for heterogeneous materials data is presented. The system integrates multimodal datasets using ontologies and knowledge graphs, enabling interoperability and FAIR (findable, accessible, interoperable, reusable) data principles. By linking data across scales and workflows, it supports reproducible, Artifitial
Doaa Mohamed, Samuel García Vázquez, Behnam Mardani, Victor Dudarev, Alfred Ludwig, Maribel Acosta, Markus Stricker   +6 more
wiley   +1 more source

High throughput methods for analyzing transition metals in proteins on a microgram scale

, 2008
Transition metals are among the most common ligands that contribute to the biochemical and physiological properties of proteins. In the course of structural proteomic projects, the detection of transition metal cofactors prior to the determination of a ...
Zamble, Deborah B, Atanassova, Anelia, Högbom, Martin,   +2 more
core  

DEVELOPMENTS AND APPLICATIONS OF HIGH-THROUGHPUT TOP-DOWN PROTEOMICS [PDF]

, 2019
Emerging technologies for liquid chromatography (LC) separations and mass spectrometry (MS) have dramatically improved the throughput of top-down proteomics, which has allowed the identification of thousands of intact proteoforms in complex biological ...
Wang, Zhe
core  

Nanopore sequencing-derived methylation biomarker prediction for methylation-specific PCR in patients with head and neck squamous cell carcinoma

Clinical Epigenetics
Background DNA methylation of CpG islands is altered in cancer cells. Hypermethylation of single CpG islands in the promoter regions of tumor-suppressor genes occurs already in the early stages of cancer.
Daria Meyer, Anne Hennig, Anna-Bawany Hums, Orlando Guntinas-Lichius, Martina Schmitz, Manja Marz   +5 more
doaj   +1 more source

Performance Analysis of Abradable Coating Systems for Aircraft Gas Turbines

Advanced Engineering Materials, EarlyView.
Three CoNiCrAlY/YSZ/MgAl2O4 abradable liner configurations on a nickel‐superalloy are evaluated by thermal‐gradient cycling and incursion tests. Laser ablation of the bondcoat and/or Y2O3‐stabilized ZrO2 (YSZ) intermediate layer increases mechanical interlocking and bonding for thick topcoats.
Hanna Heyl, Daniel Emil Mack, Martin Tandler, Susanne Schrüfer, Robert Vaßen   +4 more
wiley   +1 more source

High-throughput characterization of fluid properties to predict droplet ejection for three-dimensional inkjet printing formulations

, 2019
Inkjet printing has been used as an Additive Manufacturing (AM) method to fabricate three-dimensional (3D) structures. However, a lack of materials suitable for inkjet printing poses one of the key challenges that impedes industry from fully adopting ...
Xuesheng Chen, Roberts, Clive J., Ricky Wildman, Morgan R. Alexander, Zuoxin Zhou, Irvine, Derek, Richard Hague, Chen, Xuesheng, Wildman, Ricky, Derek Irvine, Laura Ruiz Cantu, Hague, Richard, Alexander, Morgan R., Clive J. Roberts, Ruiz Cantu, Laura, Tuck, Christopher, Christopher Tuck, Zhou, Zuoxin   +17 more
core   +1 more source