Results 171 to 180 of about 229,759 (254)

Role of RNA modifications in carcinogenesis and carcinogen damage response

Molecular Carcinogenesis, Volume 62, Issue 1, Page 24-37, January 2023., 2023
Abstract The field of epitranscriptomics encompasses the study of post‐transcriptional RNA modifications and their regulatory enzymes. Among the numerous RNA modifications, N6‐methyladenosine (m6A) has been identified as the most common internal modification of messenger RNA (mRNA).
Michelle Verghese, Emma Wilkinson, Yu‐Ying He   +2 more
wiley   +1 more source

Elucidation of intragenomic variation of ribosomal DNA sequences in the enigmatic fungal genus Ceraceosorus, including a newly described species Ceraceosorus americanus. [PDF]

IMA Fungus
Kijpornyongpan T, Noble MC, Piątek M, Lutz M, Aime MC.   +4 more
europepmc   +1 more source

Identification of New Single Nucleotide Polymorphisms Potentially Related to Small Ruminant Lentivirus Infection Susceptibility in Goats Based on Data Selected from High-Throughput Sequencing

Magdalena Materniak-Kornas, Katarzyna Ropka‐Molik, Katarzyna Piórkowska, Joanna Kowalik, Tomasz Szmatoła, Jacek Sikora, Aldona Kawęcka, Jacek Kuźmak   +7 more
openalex   +1 more source

Discovering new hub genes of dilated cardiomyopathy

ESC Heart Failure, EarlyView.
Abstract Aims Dilated cardiomyopathy (DCM) has a poor prognosis and exhibits a complex and diverse aetiology and genetic profile. The genes responsible for the pathogenesis of DCM have not been fully identified. The present study aimed to explore new hub genes of DCM by mining the human DCM databases and further by experimental validation.
Jun‐Yan Zhu, Yu Han, Jing‐Yu Yang, De‐Ping Wang, Li‐Juan Gao, Teng Sun, Yan‐Lin Feng, Zhong‐Mei He, Bin Zhou, Ji‐Min Cao   +9 more
wiley   +1 more source

Nanopore adaptive sampling accurately detects nucleotide variants and improves the characterization of large-scale rearrangement for the diagnosis of cancer predisposition. [PDF]

Clin Transl Med
Chevrier S, Richard C, Mille M, Bertrand D, Boidot R.   +4 more
europepmc   +1 more source

Ligase-catalyzed transcription and reverse-transcription of XNA-containing nucleic acid polymers using T3 DNA ligase. [PDF]

Chem Sci
Khamissi N, Korfmann C, Chaudhry A, Hili R.   +3 more
europepmc   +1 more source

Utilization of high throughput genome sequencing technology for large scale single nucleotide polymorphism discovery in red deer and Canadian elk

, 2017
Rüdiger Bräuning, P. J. Fisher, Alan McCulloch, Russell J Smithies, James F Ward, Matthew J. Bixley, Cindy Lawley, Suzanne J. Rowe, John C. McEwan, Josephine M. Pemberton   +9 more
openalex   +2 more sources

A Comprehensive Review on Capillary Electrophoresis–Mass Spectrometry in Advancing Biomolecular Research

ELECTROPHORESIS, EarlyView.
ABSTRACT This review provides an in‐depth exploration of capillary electrophoresis–mass spectrometry (CE–MS) in biomolecular research from 2020 to 2024. CE–MS emerges as a versatile and powerful tool due to its numerous advantages, facilitating the analysis of various biomolecules, including proteins, peptides, oligonucleotides, and other metabolites ...
Laura Pont, María Vergara‐Barberán, Enrique Javier Carrasco‐Correa   +2 more
wiley   +1 more source

KEAP1‐NRF2 protein–protein interaction inhibitors: Design, pharmacological properties and therapeutic potential

Medicinal Research Reviews, Volume 43, Issue 1, Page 237-287, January 2023., 2023
Abstract The transcription factor nuclear factor erythroid 2‐related factor 2 (NRF2) is considered the master regulator of the phase II antioxidant response. It controls a plethora of cytoprotective genes related to oxidative stress, inflammation, and protein homeostasis, among other processes.
Enrique Crisman, Pablo Duarte, Esteban Dauden, Antonio Cuadrado, María Isabel Rodríguez‐Franco, Manuela G. López, Rafael León   +6 more
wiley   +1 more source

Merging High-Throughput, Amplicon-Based Second and Third Generation Sequencing Data: An Integrative and Modular Data Analysis Framework for Haplotype Prediction and Output Evaluation. [PDF]

Int J Mol Sci
Mink S, Attenberger C, Busch Y, Kiefer J, Peter W, Cadamuro J, Steiert TA, Franke A, Gassner C.   +8 more
europepmc   +1 more source