Results 181 to 190 of about 62,485 (295)

Drought Response and Genetic Variation in Scots Pine Seedlings' Provenances: Insights From High-Throughput Phenotyping for Climate-Resilient Forestry. [PDF]

Evol Appl
Neuwirthová E, Stejskal J, Lhotáková Z, Korecký J, Čepl J, Nikodem A, Panzarová K, Albrechtová J, Lstibůrek M.   +8 more
europepmc   +1 more source

Single‐Cell Computational Frameworks for Quantifying BET Bromodomain Inhibitor Resistance and Screening Re‐Sensitizer Drugs in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
To combat BET inhibitor resistance in triple‐negative breast cancer, we developed two single‐cell computational frameworks. FR20 quantifies resistance by integrating ferroptosis‐related gene signatures, while D‐FR20 screens for potential re‐sensitizers.
Haizhou Liu, Mengqin Yuan, Yini Shang, Jiahao Chen, Fei Hou, Lihong Wang, Wei Jiang   +6 more
wiley   +1 more source

Near-infrared spectroscopy as a high-throughput phenotyping method for fusiform rust resistance in loblolly pine. [PDF]

Plant Phenomics
Lim-Hing S, Conrad AO, Montes CR, Gandhi KJK, Payn KG, Walker TD, Villari C.   +6 more
europepmc   +1 more source

Endocytic Control of Cell‐Autonomous and Non‐Cell‐Autonomous Functions of p53

Advanced Science, EarlyView.
NUMB Ex3‐containing isoforms localize to the plasma membrane, where they recruit p53 through SNX9 and direct it to multivesicular bodies and exosomes. Exported p53 is taken up by neighboring cells and activates nuclear programs, revealing an intercellular, exosome‐based pathway that might help establish a tumor‐suppressive microenvironment.
Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, Rosalind Helen Gunby, Salvatore Pece, Sara Sigismund, Letizia Lanzetti, Ivan Nicola Colaluca, Pier Paolo Di Fiore   +20 more
wiley   +1 more source

Integrating Dense Genotyping with High-Throughput Phenotyping Empowers the Genetic Dissection of Berry Quality and Resilience Traits in Grapevine. [PDF]

Adv Sci (Weinh)
Zhang Y, Wang Y, Henke M, Carbonell-Bejerano P, Wang Z, Bert PF, Wang Y, Li H, Kong J, Fan P, Dai Z, Liang Z.   +11 more
europepmc   +1 more source

Enhancing estimation of cover crop biomass using field-based high-throughput phenotyping and machine learning models. [PDF]

Front Plant Sci, 2023
Bai G, Koehler-Cole K, Scoby D, Thapa VR, Basche A, Ge Y.   +5 more
europepmc   +1 more source

Unraveling the Molecular Mechanisms Underlying Spontaneous Multipolar Mitosis Through CIN‐seq

Advanced Science, EarlyView.
Multipolar mitosis, a hallmark of chromosomal instability (CIN), drives tumor heterogeneity but is challenging to study in live cells. Using CIN‐seq, a single‐cell multiomics method, we profiled rare CIN events and identified mechanisms associated with viable multipolar mitosis, including PTEN attenuation, Rho GTPase‐driven cytokinesis failure, and ...
Pin‐Rui Su, Ting‐Chun Chou, Maria Teresa López‐Cascales, Junfeng Huang, Tsai‐Ying Chen, Sjoukje van Wieren, Chan Li, Cecile Beerens, Li You, Jelle Storteboom, Miao‐Ping Chien   +10 more
wiley   +1 more source

3D reconstruction enables high-throughput phenotyping and quantitative genetic analysis of phyllotaxy. [PDF]

Plant Phenomics
Davis JM, Gaillard M, Tross MC, Shrestha N, Ostermann I, Grove RJ, Li B, Benes B, Schnable JC.   +8 more
europepmc   +1 more source

Conformable Microelectrode Arrays Integrated with a Scoop‐Shaped Slide‐Well for Dynamic Electrophysiological Profiling of Patient‐Derived Cardiac Organoids

Advanced Science, EarlyView.
A flexible, ultrathin multi‐channel microelectrode array (MEA) conformally integrated onto a curved slide‐well enables stable electrical interfacing with 3D cardiac organoids. The geometry‐guided self‐alignment allows simultaneous recording of extracellular field potentials and contractile motion from irregular, beating tissues.
Ye Seul Kim, Jeonghwa Jeong, Gyeonghwa Heo, Young Woo Kwon, Jeongha Lee, Yoon Ji Jeong, Gyu Tae Park, Seongdo Jeong, Ki Won Hwang, Murim Choi, Jinhong Shin, Suck Won Hong, Jae Ho Kim   +12 more
wiley   +1 more source

High-Throughput Phenotyping for Agronomic Traits in Cassava Using Aerial Imaging. [PDF]

Plants (Basel)
Nascimento JHB, Cortes DFM, Andrade LRB, Gallis RBA, Barbosa RL, Oliveira EJ.   +5 more
europepmc   +1 more source