Results 191 to 200 of about 16,254,290 (323)

RAPA: RaspberryPi Automated Phenotyping Array provides low-cost, scalable, automated, high-throughput, in-place phenotyping

, 2014
Today, genetic data is relatively cheap, but phenotypic data is costly in time and resources. Many phenotypes are measured by hand. The full potential of next-generation sequencing will not be realized without high-throughput phenotyping.
Noll, A., Weigel, D., Wang, G., Rowan, B., Widmer, C.   +4 more
core  

Compact 9dBEs Enable Efficient and Precise Genome Editing in Mammalian Cells and In Vivo

Advanced Science, EarlyView.
As a compact type II‐D system, the Cas9d‐based platform holds great potential for in vivo applications. Through rational engineering, its derived base editors (9dBEs) enable efficient disease modeling while facilitating single‐vector AAV delivery for in vivo genome editing. These miniature tools offer a robust strategy for basic research and biomedical
Qingquan Xiao, Zhijin Tian, Luqi Weng, Kun Xu, Dingyi Han, Zhaowei Wu, Junnan Li, Shangpu Li, Qijing Zhang, Xiaohui Zhao, Guoling Li, Yinghui Wei, Zhen Gu   +12 more
wiley   +1 more source

Deep learning-based high-throughput phenotyping for tiller quantification in interspecific bentgrass hybrids using YOLOv8. [PDF]

Front Plant Sci
Ferm DW, Kim Y, Barnaby JY.
europepmc   +1 more source

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

Advanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou, Ruixi Yu, Xuan Zhou, Feng Shi, Zeyu Lin, Peng Gao, Lujia Wang, Ninghan Feng, Zhong Wu, Dawei Wang   +9 more
wiley   +1 more source

Harnessing high-throughput phenotyping and artificial intelligence for soybean breeding: From trait assessment to data-driven decisions. [PDF]

Plant Phenomics
Chagas JTB, Araújo MS, Pavan JPS, Françani AO, Ferreira GNC, Stella AA, Martinez M, Retore YI, Fregonezi BF, Martins GM, Zhao T, Zhou J, Sousa DR, Gao Y, Ji D, Gao K, Li B, Liu S, Zhao L, Pinheiro JB.   +19 more
europepmc   +1 more source

Natural‐Inspired Engineered Microalgae With Selenium Enrichment Enabled Potent Anti‐Tumor Immunity

Advanced Science, EarlyView.
Se‐Ssp was engineered as a potent immunomodulator for activating innate immunity via the TLR and cGAS‐STING pathways, therefore converting “cold” tumors into “hot” tumors to achieve high efficacy and long‐term therapeutic outcomes. ABSTRACT Immunotherapy has shed light on clinical oncology for several decades.
Yuqi Yang, Xiaowei Cai, Xiaoyan Zhong, Tian Qiu, Qinwei Lu, Jiahao Qin, Fei Gong, Yecheng Huang, Chenyu Jiang, Youdong Chen, Yuan Cheng, Liang Cheng   +11 more
wiley   +1 more source

Genomic Selection Integrated with High-Throughput Phenotyping and Speed Breeding for Smart and Greener Rice (<i>Oryza sativa</i>) Improvement. [PDF]

Genes (Basel)
Chu HD, Nguyen TQ, Nguyen LV, Chuong NN, Ha QT, Thao NTP, Anik TR, Sulieman S, Li W, Tran LP.   +9 more
europepmc   +1 more source

The Mitogen‐Activated Protein Kinase GhNTF3 Modulates the Arbuscular Mycorrhizal Symbiosis‐Immunity Trade‐Off in Cotton by Regulating Salicylic Acid Biosynthesis

Advanced Science, EarlyView.
AM symbiosis induces GhWAK13 to promote fungal colonization. GhNTF3 negatively regulates symbiosis by promoting SA biosynthesis. GhWAK13 sequesters GhNTF3 at the membrane, limiting its nuclear translocation and relieving SA‐mediated suppression. Under Verticillium stress, GhNTF3 enters the nucleus and interacts with GhJAZ6 to activate SA signaling ...
Shuangjie Jia, Jingshang Wen, Jihang Li, Meina Feng, Yiming He, Ruojun Liu, Qian Liu, Junli Zhang, Kai Cheng, Xiangyu Zhang, Xiao Zhang   +10 more
wiley   +1 more source

YOLO-based high-throughput phenotyping pipeline for soybean nodulation traits in genomic research. [PDF]

Front Plant Sci
Shivashakarappa K, Ghimire N, Wang L, Dumenyo K, Pariyar S, Busch W, Taheri A.   +6 more
europepmc   +1 more source

p300‐Mediated H3K18 Lactylation Drives Radiation‐Induced Pulmonary Fibrosis via VIRMA‐Dependent m6A Modification of GATA3

Advanced Science, EarlyView.
Radiation triggers glycolytic reprogramming in alveolar epithelial type II cells, causing pathological lactate accumulation. This metabolic stress drives p300‐mediated H3K18 lactylation at the VIRMA promoter, activating transcription. Elevated VIRMA enriches m6A on GATA3 mRNA, which YTHDF1 stabilizes, ultimately driving epithelial–mesenchymal ...
Junxuan Yi, Mingwei Wang, Duo Yu, Mingqi Zhao, Xinyan Wang, Shiqi Li, Xiaowen Han, Wei Wei, Shunzi Jin   +8 more
wiley   +1 more source