Results 41 to 50 of about 14,831,592 (247)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

High‐throughput phenotyping platforms for pulse crop biofortification

Plants, People, Planet
Societal Impact Statement Pulse crops, including dry pea, lentil, and chickpea, are rich sources of protein, low digestible carbohydrates, and micronutrients.
Amod Madurapperumage, M. Z. Naser, Lucas Boatwright, William Bridges, George Vandemark, Dil Thavarajah   +5 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Wellcounter: Automated high‐throughput phenotyping for aquatic microinvertebrates

Methods in Ecology and Evolution
Using phenotypic information extracted from digital images through automated computer vision analysis has become a promising avenue in ecological and evolutionary research.
Claus‐Peter Stelzer, Dominique Groffman   +1 more
doaj   +1 more source

Proximal Active Optical Sensing Operational Improvement for Research Using the CropCircle ACS-470, Implications for Measurement of Normalized Difference Vegetation Index (NDVI)

Sensors, 2023
Active radiometric reflectance is useful to determine plant characteristics in field conditions. However, the physics of silicone diode-based sensing are temperature sensitive, where a change in temperature affects photoconductive resistance.
Matthew M. Conley, Alison L. Thompson, Reagan Hejl   +2 more
doaj   +1 more source

Acknowledgement to Reviewers of High-Throughput in 2017

, 2018
Peer review is an essential part in the publication process, ensuring that High-Throughput maintains high quality standards for its published papers [...
High-Throughput Editorial Office
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

High-Throughput Phenotyping: Application in Maize Breeding

AgriEngineering
In breeding programs, the demand for high-throughput phenotyping is substantial as it serves as a crucial tool for enhancing technological sophistication and efficiency.
Ewerton Lélys Resende, Adriano Teodoro Bruzi, Everton da Silva Cardoso, Vinícius Quintão Carneiro, Vitório Antônio Pereira de Souza, Paulo Henrique Frois Correa Barros, Raphael Rodrigues Pereira   +6 more
doaj   +1 more source

High Throughput Phenotyping in Plant Breeding

, 2022
An introduction to plant breeding and high throughput phenotyping. This lesson outlines the steps and goals of the plant breeding process and identifies areas that can be improved with high throughput phenotyping methods.
Mick, Catherine, Lee, Don, Sandall, Leah, Frels, Katherine Anna, Ge, Yufeng   +4 more
core  

High-throughput phenotyping to dissect genotypic differences in safflower for drought tolerance

, 2021
Drought is one of the most severe and unpredictable abiotic stresses, occurring at any growth stage and affecting crop yields worldwide. Therefore, it is essential to develop drought tolerant varieties to ensure sustainable crop production in an ever ...
German Spangenberg (9477560), S Joshi (11215038), Surya Kant (10798998), E Thoday-Kennedy (11215035), Hans Daetwyler (4608577), Matthew Hayden (9481265)   +5 more
core   +1 more source